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Terminated Phase 2 Interventional

Efficacy of MT-401 in Patients With AML Following Stem Cell Transplant

ClinicalTrials.gov ID: NCT04511130

Public ClinicalTrials.gov record NCT04511130. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 3:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of Donor-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-401) Administered to Patients With Acute Myeloid Leukemia (AML) Following Hematopoietic Stem Cell Transplantation

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is a Phase 2 multicenter study with a Safety Lead-in evaluating safety and efficacy of MT-401 administration to patients with AML, who have received their first allogeneic HSCT. The dose administered is 50 x 10\^6 cells (flat dosing).

Study identification

NCT ID
NCT04511130
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Marker Therapeutics, Inc.
Industry
Enrollment
92 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 14, 2020 (Actual)
Primary completion
Mar 1, 2024 (Actual)
Completion
Mar 1, 2024 (Actual)
Last update posted
Oct 30, 2025

2020 – 2024

United States locations

U.S. sites
18
U.S. states
12
U.S. cities
16
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35249 —
City of Hope National Medical Center Duarte California 91010 —
Moores Cancer Center at University of Californa San Diego La Jolla California 92093 —
UCLA Department of Medicine Los Angeles California 90095 —
Yale Cancer Center New Haven Connecticut 06519 —
Mayo Clinical Cancer Center-Florida Jacksonville Florida 32224 —
Moffitt Cancer Center Tampa Florida 33612 —
Winship Cancer Institute of Emory University Atlanta Georgia 303222 —
University of Chicago Chicago Illinois 77027 —
University of Iowa Hospitals & Clinics Iowa City Iowa 52242 —
Mayo Clinic Cancer Center-Rochester Rochester Minnesota 55905 —
John Theurer Cancer Center at Hackensack UMC Hackensack New Jersey 07601 —
Weill Cornell Medicine | NewYork-Presbyterian New York New York 10027 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Montefiore Medical Center The Bronx New York 10467 —
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195 —
Baylor College of Medicine Houston Texas 77030 —
MD Anderson Cancer Center Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04511130, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 30, 2025 · Synced Oct 16, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04511130 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →