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Terminated Phase 2 Interventional

Efficacy of MT-401 in Patients With AML Following Stem Cell Transplant

ClinicalTrials.gov ID: NCT04511130

Public ClinicalTrials.gov record NCT04511130. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 1:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of Donor-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-401) Administered to Patients With Acute Myeloid Leukemia (AML) Following Hematopoietic Stem Cell Transplantation

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is a Phase 2 multicenter study with a Safety Lead-in evaluating safety and efficacy of MT-401 administration to patients with AML, who have received their first allogeneic HSCT. The dose administered is 50 x 10\^6 cells (flat dosing).

Study identification

NCT ID
NCT04511130
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Marker Therapeutics, Inc.
Industry
Enrollment
92 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 13, 2020
Primary completion
Feb 29, 2024
Completion
Feb 29, 2024
Last update posted
Oct 29, 2025

2020 – 2024

United States locations

U.S. sites
18
U.S. states
12
U.S. cities
16
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35249
City of Hope National Medical Center Duarte California 91010
Moores Cancer Center at University of Californa San Diego La Jolla California 92093
UCLA Department of Medicine Los Angeles California 90095
Yale Cancer Center New Haven Connecticut 06519
Mayo Clinical Cancer Center-Florida Jacksonville Florida 32224
Moffitt Cancer Center Tampa Florida 33612
Winship Cancer Institute of Emory University Atlanta Georgia 303222
University of Chicago Chicago Illinois 77027
University of Iowa Hospitals & Clinics Iowa City Iowa 52242
Mayo Clinic Cancer Center-Rochester Rochester Minnesota 55905
John Theurer Cancer Center at Hackensack UMC Hackensack New Jersey 07601
Weill Cornell Medicine | NewYork-Presbyterian New York New York 10027
Memorial Sloan Kettering Cancer Center New York New York 10065
Montefiore Medical Center The Bronx New York 10467
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195
Baylor College of Medicine Houston Texas 77030
MD Anderson Cancer Center Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04511130, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 29, 2025 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04511130 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →