ClinicalTrials.gov record
A Dose-Ranging Study With Vupanorsen (TRANSLATE-TIMI 70)
ClinicalTrials.gov ID: NCT04516291
Public ClinicalTrials.gov record NCT04516291. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging Study to Assess the Efficacy, Safety, and Tolerability of Vupanorsen (PF-07285557) in Statin-Treated Participants With Dyslipidemia
Study identification
- NCT ID
- NCT04516291
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 286 participants
Conditions and interventions
Conditions
Interventions
- Vupanorsen Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 27, 2020
- Primary completion
- Sep 28, 2021
- Completion
- Dec 5, 2021
- Last update posted
- Oct 3, 2022
2020 – 2021
United States locations
- U.S. sites
- 59
- U.S. states
- 20
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Horizon Clinical Research Associates, PLLC | Gilbert | Arizona | 85295 | — |
| Scottsdale Medical Imaging Research, LLC | Gilbert | Arizona | 85297 | — |
| CARTI | Little Rock | Arkansas | 72205 | — |
| Atria Clinical Research | Little Rock | Arkansas | 72209 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| Diagnostic Radiological Imaging | Sacramento | California | 95825 | — |
| West Coast Radiology | Santa Ana | California | 92705 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Tower Radiology Parsons | Brandon | Florida | 33511 | — |
| Tower Radiology | Brandon | Florida | 33511 | — |
| Innovative Research of West Florida, Inc. | Clearwater | Florida | 33756 | — |
| Westside Center for Clinical Research | Jacksonville | Florida | 32205 | — |
| Borland-Groover Clinic | Jacksonville | Florida | 32256 | — |
| Precision Imaging Centers | Jacksonville | Florida | 32256 | — |
| Care Partners Clinical Research, LLC | Jacksonville | Florida | 32277 | — |
| Advanced Research Institute, Inc. | New Port Richey | Florida | 34653 | — |
| Sand Lakes Imaging | Orlando | Florida | 32819 | — |
| St Johns Center for Clinical Research | Saint Augustine | Florida | 32086 | — |
| Clinical Research of Central Florida | Winter Haven | Florida | 33880 | — |
| Alliance for Multispecialty Research, LLC | El Dorado | Kansas | 67042 | — |
| Susan B. Allen Memorial Hospital | El Dorado | Kansas | 67042 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Heartland Imaging | Louisville | Kentucky | 40222 | — |
| Maryland Cardiovascular Specialists | Baltimore | Maryland | 21229 | — |
| Seton Imaging Center | Baltimore | Maryland | 21229 | — |
| Lahey Clinic Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Pentucket Medical Associates | Haverhill | Massachusetts | 01830 | — |
| Regions Hospital - HealthPartners | Saint Paul | Minnesota | 55101 | — |
| Viable Research Management LLC | Henderson | Nevada | 89014 | — |
| Pueblo Medical Imaging | Henderson | Nevada | 89074 | — |
| Capital Cardiology Associates | Albany | New York | 12211 | — |
| ImageCare Latham | Latham | New York | 12110 | — |
| Randolph Health Internal Medicine | Asheboro | North Carolina | 27203 | — |
| Randolph Health MRI Center | Asheboro | North Carolina | 27205 | — |
| PMG Research of Raleigh, LLC d/b/a PMG Research of Cary | Cary | North Carolina | 27518 | — |
| Wake Radiology | Cary | North Carolina | 27518 | — |
| Accellacare - Raleigh | Raleigh | North Carolina | 27609 | — |
| PMG Research of Raleigh, LLC | Raleigh | North Carolina | 27609 | — |
| Wake Radiology Diagnostic Imaging Inc | Raleigh | North Carolina | 27609 | — |
| PMG Research of Winston-Salem, LLC | Winston-Salem | North Carolina | 27103 | — |
| Hightop Medical Research Center | Cincinnati | Ohio | 45224 | — |
| Imaging Research Center-Cincinnati Children's | Cincinnati | Ohio | 45229 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Clermont Radiology Orangeburg | Orangeburg | South Carolina | 29118 | — |
| South Carolina Clinical Research LLC | Orangeburg | South Carolina | 29118 | — |
| Tennessee Center for Clinical Trials | Tullahoma | Tennessee | 37388 | — |
| Tullahoma HMA, LLC d\b\a Tennova HealthCare Harton | Tullahoma | Tennessee | 37388 | — |
| Dallas Diabetes Research Center | Dallas | Texas | 75230 | — |
| Southwest Diagnostic Imaging Center | Dallas | Texas | 75231 | — |
| SimonMed Houston | Houston | Texas | 77030 | — |
| Southwest Clinical Trials | Houston | Texas | 77074 | — |
| Medical Center Hospital | Odessa | Texas | 79761 | — |
| Permian Research Foundation | Odessa | Texas | 79761 | — |
| J. Lewis Research, Inc. / Foothill Family Clinic South | Salt Lake City | Utah | 84121 | — |
| National Clinical Research, Inc. | Richmond | Virginia | 23294 | — |
| Rainier Clinical Research Center | Renton | Washington | 98057 | — |
| Bellevue Medical Imaging | Seattle | Washington | 98166 | — |
| Universal Research Group, LLC | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04516291, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 3, 2022 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04516291 live on ClinicalTrials.gov.