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Completed Phase 3 Interventional Accepts healthy volunteers Results available

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

ClinicalTrials.gov ID: NCT04516746

Public ClinicalTrials.gov record NCT04516746. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 12:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Randomized, Double-blind, Placebo-controlled Multicenter Study in Adults, to Determine the Safety, Efficacy, and Immunogenicity of AZD1222, a Non-replicating ChAdOx1 Vector Vaccine, for the Prevention of COVID-19

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The aim of the study is to assess the safety, efficacy, and immunogenicity of AZD1222 for the prevention of COVID-19.

Study identification

NCT ID
NCT04516746
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
32,450 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years to 130 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 28, 2020 (Actual)
Primary completion
Mar 5, 2021 (Actual)
Completion
Feb 10, 2023 (Actual)
Last update posted
Feb 5, 2024

2020 – 2023

United States locations

U.S. sites
78
U.S. states
39
U.S. cities
69
Facility City State ZIP Site status
Research Site Phoenix Arizona 85018 —
Research Site Scottsdale Arizona 85258 —
Research Site Little Rock Arkansas 72212 —
Research Site Berkeley California 94705 —
Research Site El Centro California 92243 —
Research Site Los Angeles California 90033 —
Research Site Los Angeles California 90095 —
Research Site San Diego California 92103 —
Research Site San Diego California 92134 —
Research Site San Francisco California 94102 —
Research Site San Francisco California 94158 —
Research Site Torrance California 90502 —
Research Site Denver Colorado 80204 —
Research Site Danbury Connecticut 06810 —
Research Site Coral Gables Florida 33134 —
Research Site Lake Worth Florida 33462 —
Research Site Miami Lakes Florida 33016 —
Research Site Orlando Florida 32803 —
Research Site Honolulu Hawaii 96814 —
Research Site Meridian Idaho 83642 —
Research Site Chicago Illinois 60612 —
Research Site Indianapolis Indiana 46202 —
Research Site Ankeny Iowa 50023 —
Research Site Fairway Kansas 66205 —
Research Site Kansas City Kansas 66160 —
Research Site Wichita Kansas 67207 —
Research Site Wichita Kansas 67214 —
Research Site Lexington Kentucky 40509 —
Research Site Lake Charles Louisiana 70601 —
Research Site Monroe Louisiana 71201 —
Research Site Baltimore Maryland 21201 —
Research Site Baltimore Maryland 21205 —
Research Site Bethesda Maryland 20889 —
Research Site Boston Massachusetts 02111 —
Research Site Boston Massachusetts 02215 —
Research Site Ann Arbor Michigan 48109 —
Research Site Royal Oak Michigan 48073 —
Research Site Minneapolis Minnesota 55425 —
Research Site Gulfport Mississippi 39503 —
Research Site Butte Montana 59701 —
Research Site Portsmouth New Hampshire 03801 —
Research Site Berlin New Jersey 08009 —
Research Site Albuquerque New Mexico 87102 —
Research Site Brooklyn New York 11220 —
Research Site Mineola New York 11501 —
Research Site New York New York 10010 —
Research Site New York New York 10016 —
Research Site New York New York 10032 —
Research Site Rochester New York 14621 —
Research Site Rochester New York 14642 —
Research Site The Bronx New York 10467 —
Research Site Valhalla New York 10595 —
Research Site Durham North Carolina 27710 —
Research Site Cincinnati Ohio 45229 —
Research Site Columbus Ohio 43210 —
Research Site Yukon Oklahoma 73099 —
Research Site Portland Oregon 97239 —
Research Site Pittsburgh Pennsylvania 15232 —
Research Site Warwick Rhode Island 02886 —
Research Site Charleston South Carolina 29425 —
Research Site North Charleston South Carolina 29406 —
Research Site Spartanburg South Carolina 29303 —
Research Site Knoxville Tennessee 37920 —
Research Site Nashville Tennessee 37203 —
Research Site Austin Texas 78745 —
Research Site Dallas Texas 75208 —
Research Site Fort Sam Houston Texas 78234 —
Research Site Houston Texas 77030 —
Research Site McAllen Texas 78504 —
Research Site San Antonio Texas 78236 —
Research Site Spring Texas 77381 —
Research Site West Jordan Utah 84088 —
Research Site Burlington Vermont 05401 —
Research Site Fort Belvoir Virginia 22060 —
Research Site Richmond Virginia 23226 —
Research Site Seattle Washington 98109 —
Research Site South Charleston West Virginia 25309 —
Research Site Madison Wisconsin 53792-5666 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04516746, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 5, 2024 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04516746 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →