Efficacy and Safety of GMRx2 Compared to Placebo for the Treatment of Hypertension
Public ClinicalTrials.gov record NCT04518306. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of GMRx2 (a Single Pill Combination Containing Telmisartan/Amlodipine/Indapamide) Compared to Placebo for the Treatment of Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Recent hypertension guidelines recommend combination therapy as initial treatment for many or most patients. Several trials suggest triple low-dose combination therapy may be highly effective in terms of achieving blood pressure control without increasing adverse effects. This trial is designed to investigate the efficacy and safety of GMRx2 in participants with high blood pressure compared to placebo.
Study identification
- NCT ID
- NCT04518306
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 755 participants
Conditions and interventions
Conditions
Interventions
- Telmisartan 10 mg/amlodipine 1.25 mg/indapamide 0.625 mg Drug
- Telmisartan 20 mg/amlodipine 2.5 mg/indapamide 1.25 mg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 14, 2021 (Actual)
- Primary completion
- Sep 19, 2023 (Actual)
- Completion
- Oct 18, 2023 (Actual)
- Last update posted
- Jun 3, 2025
2021 – 2023
United States locations
- U.S. sites
- 23
- U.S. states
- 8
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Elite Clinical Studies | Phoenix | Arizona | 85018 | — |
| Headlands Research | Scottsdale | Arizona | 85260 | — |
| Quality of Life Medical & Research Centers, LLC | Tucson | Arizona | 85712 | — |
| Valiance Clinical Research | South Gate | California | 90280 | — |
| Valiance Clinical Research | Tarzana | California | 91356 | — |
| Clinical Research of Brandon | Brandon | Florida | 33511 | — |
| Inpatient Research Clinic | Hialeah | Florida | 33013 | — |
| Suncoast Research Group | Miami | Florida | 33135 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| Ocala Research Institute | Ocala | Florida | 34471 | — |
| Altus Research, Inc | Palm Beach | Florida | 33461 | — |
| Suncoast Research Associates | St. Petersburg | Florida | 33173 | — |
| Accel Research | St. Petersburg | Florida | 33709 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| Precision Research Center | Tampa | Florida | 33603 | — |
| Buckhead Primary Care Research | Snellville | Georgia | 30078 | — |
| Meridian Clinical Research | Baton Rouge | Louisiana | 70809 | — |
| The University of Tennessee Health Science Center | Memphis | Tennessee | 38105 | — |
| Synergy Groups Medical | Houston | Texas | 77036 | — |
| Synergy Groups Medical | Houston | Texas | 77087 | — |
| Synergy Groups Medical | Missouri City | Texas | 77459 | — |
| North Hills Medical Research | North Richland Hills | Texas | 76180 | — |
| Meridian Clinical Research | Portsmouth | Virginia | 23703 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04518306, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 3, 2025 · Synced Oct 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04518306 live on ClinicalTrials.gov.