Study to Evaluate the Efficacy and Safety of CTP-543 in Adults With Moderate to Severe Alopecia Areata (THRIVE-AA1)
Public ClinicalTrials.gov record NCT04518995. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata (THRIVE-AA1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study evaluates the safety and effectiveness of an investigational study drug (called CTP-543) in adults (18 years and older) who have 50% or greater scalp hair loss.
Study identification
- NCT ID
- NCT04518995
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 706 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 23, 2020 (Actual)
- Primary completion
- Apr 19, 2022 (Actual)
- Completion
- Apr 19, 2022 (Actual)
- Last update posted
- May 3, 2023
2020 – 2022
United States locations
- U.S. sites
- 47
- U.S. states
- 23
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Total Skin and Beauty Dermatology Center | Birmingham | Alabama | 35205 | — |
| Kern Research, Inc. | Bakersfield | California | 93301 | — |
| California Dermatology & Clinical Research Institute | Encinitas | California | 92024 | — |
| UC Irvine Dermatology Clinical Research Center | Irvine | California | 92697 | — |
| Quest Dermatology Research | Northridge | California | 91324 | — |
| Kaiser Permanente | Oakland | California | 94611 | — |
| Kaiser Permanente South Sacramento | Sacramento | California | 95823 | — |
| Kaiser Permanente | San Francisco | California | 94118 | — |
| Colorado Center for Dermatology and Skin Surgery | Centennial | Colorado | 80111 | — |
| Colorado Medical Research Center | Denver | Colorado | 80210 | — |
| Yale University, Church Street Research Unit | New Haven | Connecticut | 06519 | — |
| Lenus Research & Medical Group, LLC | Sweetwater | Florida | 33172 | — |
| Clinical Research Trials of Florida, Inc. | Tampa | Florida | 33607 | — |
| Forward Clinical Trials Inc. | Tampa | Florida | 33624 | — |
| Denova Research | Chicago | Illinois | 60611 | — |
| Northwestern Memorial Hospital, Department of Dermatology | Chicago | Illinois | 60611 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46250 | — |
| DS Research | New Albany | Indiana | 47150 | — |
| The Indiana Clinical Trials Center, PC | Plainfield | Indiana | 46168 | — |
| DS Research | Louisville | Kentucky | 40241 | — |
| Qualmedica Research LLC | Owensboro | Kentucky | 42301 | — |
| Massachusetts General Hospital - Clinic | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Clarkston Skin Research | Clarkston | Michigan | 48346 | — |
| Minnesota Clinical Study Center | Fridley | Minnesota | 55432 | — |
| University of Minnesota Department of Dermatology | Minneapolis | Minnesota | 55455 | — |
| Skin Laser and Surgery Specialists of NJ | Hackensack | New Jersey | 07601 | — |
| Sadick Research Group | New York | New York | 10075 | — |
| Darst Dermatology | Charlotte | North Carolina | 28277 | — |
| Dermatology Specialists of Charlotte | Charlotte | North Carolina | 28277 | — |
| Wake Forest University Health Sciences, Department of Dermatology | Winston-Salem | North Carolina | 27157 | — |
| Bexley Dermatology Research | Bexley | Ohio | 43209 | — |
| Vital Prospects Clinical Research Institute, P.C. | Tulsa | Oklahoma | 74136 | — |
| Northwest Dermatology Institute | Portland | Oregon | 97210 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Dermatology Associates Of Plymouth Meeting | Plymouth Meeting | Pennsylvania | 19462 | — |
| PEAK Research | Upper Saint Clair | Pennsylvania | 15241 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Clinical Research Center of the Carolinas | Charleston | South Carolina | 29407 | — |
| Palmetto Clinical Trial Services | Fountain Inn | South Carolina | 29644 | — |
| Bellaire Dermatology Associates | Bellaire | Texas | 77401 | — |
| Dermatology Treatment and Research Center | Dallas | Texas | 75230 | — |
| Austin Institute for Clinical Research, Inc. | Houston | Texas | 77056 | — |
| Austin Institute for Clinical Research, Inc. | Pflugerville | Texas | 78660 | — |
| Dermatology Clinical Research Center of San Antonio | San Antonio | Texas | 78229 | — |
| West End Dermatology Associates | Richmond | Virginia | 23233 | — |
| Clinical Investigation Specialists, Inc. | Kenosha | Wisconsin | 53144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04518995, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2023 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04518995 live on ClinicalTrials.gov.