A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the Knee
Public ClinicalTrials.gov record NCT04520607. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Long-Term Extension Study Evaluating the Safety and Efficacy of Lorecivivint in Subjects With Osteoarthritis of the Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study OA-07 was a randomized, double-blind, placebo-controlled, Phase 3, multicenter, 2-year clinical trial that enrolled subjects from the recently completed Study OA-11 (NCT03928184). The first 48 weeks of OA-07 the trial was placebo-controlled with subjects receiving the same randomized treatment received in OA-11. Investigators, research staff and subjects remained blinded to treatment allocation. At Week 48, all subjects were administered LOR in the open-label portion of the trial.
Study identification
- NCT ID
- NCT04520607
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 276 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 41 Years to 81 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 25, 2020 (Actual)
- Primary completion
- Jun 30, 2023 (Actual)
- Completion
- Jun 30, 2023 (Actual)
- Last update posted
- Mar 24, 2026
2020 – 2023
United States locations
- U.S. sites
- 42
- U.S. states
- 20
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Tucson | Arizona | 85712 | — |
| Research Site | Anaheim | California | 92805 | — |
| Research Site | Pomona | California | 91767 | — |
| Research Site | San Diego | California | 92103 | — |
| Research Site | Thousand Oaks | California | 91360 | — |
| Research Site | Denver | Colorado | 80209 | — |
| Research Site | Hialeah | Florida | 33016 | — |
| Research Site | Miami | Florida | 33173 | — |
| Research Site | Miami Lakes | Florida | 33014 | — |
| Research Site | Port Orange | Florida | 32127 | — |
| Research Site | West Palm Beach | Florida | 33409 | — |
| Research Site | Winter Haven | Florida | 33880 | — |
| Research Site | Winter Park | Florida | 32789 | — |
| Research Site | Newnan | Georgia | 30265 | — |
| Research Site | Woodstock | Georgia | 30189 | — |
| Research Site | Gurnee | Illinois | 60031 | — |
| Research Site | Oak Brook | Illinois | 60523 | — |
| Research Site | Valparaiso | Indiana | 46383 | — |
| Research Site | New Orleans | Louisiana | 70124 | — |
| Research Site | Bay City | Michigan | 48706 | — |
| Research Site | Troy | Michigan | 48085 | — |
| Research Site | Hazelwood | Missouri | 63042 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | Omaha | Nebraska | 68114 | — |
| Research Site | Hartsdale | New York | 10530 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | Rochester | New York | 14609 | — |
| Research Site | Charlotte | North Carolina | 28209 | — |
| Research Site | Salisbury | North Carolina | 28144 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Cincinnati | Ohio | 45242 | — |
| Research Site | Columbus | Ohio | 43235 | — |
| Research Site | Oklahoma City | Oklahoma | 73103 | — |
| Research Site | Fort Mill | South Carolina | 29707 | — |
| Research Site | Mt. Pleasant | South Carolina | 29464 | — |
| Research Site | Rapid City | South Dakota | 57702 | — |
| Research Site | Carrollton | Texas | 75007 | — |
| Research Site | Plano | Texas | 75075 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | Draper | Utah | 84020 | — |
| Research Site | Salt Lake City | Utah | 84107 | — |
| Research Site | Charlottesville | Virginia | 22911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04520607, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 24, 2026 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04520607 live on ClinicalTrials.gov.