ESSENCE 2: CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)
Public ClinicalTrials.gov record NCT04523129. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-center, Randomized, Double-masked, Vehicle-controlled Clinical Trial to Assess the Efficacy and Safety of Topical CyclASol® for the Treatment of Dry Eye Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this pivotal trial is to assess the efficacy, safety and tolerability of CyclASol in comparison to the vehicle for the treatment of signs and symptoms of Dry Eye Disease (DED).
Study identification
- NCT ID
- NCT04523129
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 834 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 5, 2020 (Actual)
- Primary completion
- Sep 3, 2021 (Actual)
- Completion
- Oct 8, 2021 (Actual)
- Last update posted
- Mar 10, 2023
2020 – 2021
United States locations
- U.S. sites
- 27
- U.S. states
- 19
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CYS-004 Investigational Site | Phoenix | Arizona | 85032 | — |
| CYS-004 Investigational Site | Los Angeles | California | 90013 | — |
| CYS-004 Investigational Site | Newport Beach | California | 92663 | — |
| CYS-004 Investigational Site | Santa Ana | California | 92705 | — |
| CYS-004 Investigational Site | Colorado Springs | Colorado | 80907 | — |
| CYS-004 Investigational Site | Fort Lauderdale | Florida | 33309 | — |
| CYS-004 Investigational Site | Chicago | Illinois | 60619 | — |
| CYS-004 Investigational Site | Carmel | Indiana | 46290 | — |
| CYS-004 Investigational Site | Indianapolis | Indiana | 46240 | — |
| CYS-004 Investigational site | Louisville | Kentucky | 40206 | — |
| CYS-004 Investigational Site | Andover | Massachusetts | 01810 | — |
| CYS-004 Investigational Site | Raynham | Massachusetts | 02767 | — |
| CYS-004 Investigational Site | Medina | Minnesota | 55364 | — |
| CYS-004 Investigational Site | Kansas City | Missouri | 64111 | — |
| CYS-004 Investigation Site | Kansas City | Missouri | 64154 | — |
| CYS-004 Investigational Site | Henderson | Nevada | 89052 | — |
| CYS-004 Investigational Site | Raleigh | North Carolina | 27603 | — |
| CYS-004 Investigational Site | Shelby | North Carolina | 28150 | — |
| CYS-004 Investigational Site | Fargo | North Dakota | 58103 | — |
| CYS-004 Investigational Site | Cranberry Township | Pennsylvania | 16066 | — |
| CYS-004 Investigational Site | Warwick | Rhode Island | 02886 | — |
| CYS-004 Investigational Site | Memphis | Tennessee | 38119 | — |
| CYS-004 Investigational Site | Smyrna | Tennessee | 37167 | — |
| CYS-004 Investigational Site | Layton | Utah | 84041 | — |
| CYS-004 Investigational site | Ogden | Utah | 84403 | — |
| CYS-004 Investigational Site | Lynchburg | Virginia | 24502 | — |
| CYS-004 Investigational Site | Seattle | Washington | 98119 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04523129, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 10, 2023 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04523129 live on ClinicalTrials.gov.