A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD
Public ClinicalTrials.gov record NCT04535986. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ensifentrine Over 24 Weeks (With a 48-week Safety Subset) in Subjects With Moderate to Severe COPD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of ensifentrine in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
Study identification
- NCT ID
- NCT04535986
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
- Industry
- Enrollment
- 763 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 29, 2020 (Actual)
- Primary completion
- Sep 12, 2022 (Actual)
- Completion
- Dec 2, 2022 (Actual)
- Last update posted
- Nov 13, 2023
2020 – 2022
United States locations
- U.S. sites
- 39
- U.S. states
- 17
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Medical Group | Peoria | Arizona | 85381 | — |
| AMR Tempe | Tempe | Arizona | 85281 | — |
| Beach Physicians Medical Group | Huntington Beach | California | 92647 | — |
| Downtown LA Research Center, Inc. | Los Angeles | California | 90017 | — |
| Clinical Research of West Florida, Inc. | Clearwater | Florida | 33765 | — |
| St. Francis Medical Institute | Clearwater | Florida | 33765 | — |
| Qway Research, LLC | Hialeah | Florida | 33010 | — |
| Multi-Specialty Research Associates, Inc. | Lake City | Florida | 32055 | — |
| Elite Clinical Research | Miami | Florida | 33144 | — |
| Global Research Solutions Corp | Miami | Florida | 33144 | — |
| Phoenix Medical Research | Miami | Florida | 33165 | — |
| Florida Institute for Clinical Research | Orlando | Florida | 32825 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| Clinical Research of West Florida, Inc. | Tampa | Florida | 33606 | — |
| iResearch Atlanta, LLC | Decatur | Georgia | 30030 | — |
| IACT Health | Rincon | Georgia | 31326 | — |
| In-Quest Medical Research, LLC | Suwanee | Georgia | 30024 | — |
| John Hopkins University School of Medicine | Baltimore | Maryland | 21224 | — |
| Pulmonary Research Institute of SE Michigan | Farmington Hills | Michigan | 48336 | — |
| Midwest Chest Consultants | Saint Charles | Missouri | 63301 | — |
| The Clinical Research Center, LLC | St Louis | Missouri | 63141 | — |
| Sierra Clinical Research | Las Vegas | Nevada | 89106 | — |
| Alliance for Multispecialty Research, LLC | Las Vegas | Nevada | 89119 | — |
| IMA Clinical Research, LLC | New York | New York | 10036 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Remington Davis Clinical Research | Columbus | Ohio | 43215 | — |
| Velocity Clinical Research - Grants Pass | Grants Pass | Oregon | 97527 | — |
| Clinical Research Associates of Central PA, LLC | DuBois | Pennsylvania | 15801 | — |
| University of Pittsburgh Physicians, Emphysema/COPD Research Center | Pittsburgh | Pennsylvania | 15213 | — |
| Medtrial | Columbia | South Carolina | 29204 | — |
| MDFirst Research | Lancaster | South Carolina | 29720 | — |
| Chattanooga Research & Medicine (CHARM) | Chattanooga | Tennessee | 37404 | — |
| MultiSpecialty Clinical Research, Inc. | Johnson City | Tennessee | 37601 | — |
| New Phase Research Development | Knoxville | Tennessee | 37909 | — |
| West Houston Clinical Research Services | Houston | Texas | 77055 | — |
| LinQ Research, LLC | Pearland | Texas | 77584 | — |
| Sherman Clinical Research | Sherman | Texas | 75092 | — |
| Pulmonary Research of Abingdon, LLC | Abingdon | Virginia | 24210 | — |
| TPMG Clinical Research Williamsburg | Williamsburg | Virginia | 23188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 83 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04535986, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 13, 2023 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04535986 live on ClinicalTrials.gov.