A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD
Public ClinicalTrials.gov record NCT04542057. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ensifentrine Over 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
Study identification
- NCT ID
- NCT04542057
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
- Industry
- Enrollment
- 790 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 22, 2020 (Actual)
- Primary completion
- May 3, 2022 (Actual)
- Completion
- Jul 6, 2022 (Actual)
- Last update posted
- Oct 16, 2023
2020 – 2022
United States locations
- U.S. sites
- 77
- U.S. states
- 20
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Wright Clinical Research, LLC | Alabaster | Alabama | 35007 | — |
| SEC Clinical Research | Andalusia | Alabama | 36420 | — |
| Jasper Summit Research LLC | Jasper | Alabama | 35501 | — |
| Pulmonary Associates Clinical Trials | Phoenix | Arizona | 85006 | — |
| Elite Clinical Studies LLC | Phoenix | Arizona | 85018 | — |
| Clinical Research Institute of Arizona, LLC | Sun City West | Arizona | 85375 | — |
| Premier Medical Group | Bakersfield | California | 93309 | — |
| Antelope Valley Clinical Trials | Lancaster | California | 93534 | — |
| Downtown LA Research Center, Inc. | Los Angeles | California | 90017 | — |
| UCLA Medical Center | Los Angeles | California | 90095 | — |
| California Medical Research Associates | Northridge | California | 91324 | — |
| Center for Clinical Trials of Sacramento, Inc. | Sacramento | California | 95823 | — |
| Integrated Research Center | San Diego | California | 92117 | — |
| Institute of HealthCare Assessment, Inc. | San Diego | California | 92120 | — |
| Alpine Clinical Research Center | Boulder | Colorado | 80301 | — |
| Innovative Research of West Florida | Clearwater | Florida | 33756 | — |
| Clinical Research of West Florida, Inc. | Clearwater | Florida | 33765 | — |
| Accel Research Sites - DeLand Clinical Research Unit | DeLand | Florida | 32720 | — |
| Riverside Clinical Research | Edgewater | Florida | 32132 | — |
| Medical Research of Central Florida | Leesburg | Florida | 34748 | — |
| Axcess Medical Research | Loxahatchee Groves | Florida | 13005 | — |
| Research Institute of South Florida | Miami | Florida | 33173 | — |
| Advanced Medical Research Institute | Miami | Florida | 33174 | — |
| Clinical Trials of Florida. LLC | Miami | Florida | 33186 | — |
| South Medical Research Group, Inc. | Miami | Florida | 33186 | — |
| ProCare Clinical Research | Miami Gardens | Florida | 33014 | — |
| HMD Research, LLC | Orlando | Florida | 32819 | — |
| Florida Institute for Clinical Research | Orlando | Florida | 32825 | — |
| Sarasota Clinical Research | Sarasota | Florida | 34239 | — |
| Coastal Pulmonary Critical Care | St. Petersburg | Florida | 33704 | — |
| Pasadena Center for Medical Research, LLC | St. Petersburg | Florida | 33707 | — |
| Clinical Research of West Florida, Inc. | Tampa | Florida | 33606 | — |
| Clinical Research Trials of Florida, Inc. | Tampa | Florida | 33607 | — |
| Florida Pulmonary Research Institute, LLC | Winter Park | Florida | 32789 | — |
| AMR New Orleans | New Orleans | Louisiana | 70119 | — |
| Genesis Clin RES& Consulting | Fall River | Massachusetts | 02723 | — |
| Minnesota Lung Center | Edina | Minnesota | 55435 | — |
| Minnesota Lung Center | Woodbury | Minnesota | 55125 | — |
| Midwest Chest Consultants | Saint Charles | Missouri | 63301 | — |
| Montana Medical Research Inc. | Missoula | Montana | 59808 | — |
| Mid Hudson Medical Research | New Windsor | New York | 12553 | — |
| CHEAR Center LLC | The Bronx | New York | 10455 | — |
| Carolina Clinical Research | Charlotte | North Carolina | 28273 | — |
| American Health Research | Charlotte | North Carolina | 28277 | — |
| Clinical Research of Gastonia | Gastonia | North Carolina | 28054 | — |
| PharmQuest LLC | Greensboro | North Carolina | 27408 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Clinical Research of Lake Norman | Mooresville | North Carolina | 28117 | — |
| Carolina Research Center, Inc. | Shelby | North Carolina | 28150 | — |
| Aventiv Research Inc. | Columbus | Ohio | 43213 | — |
| Remington Davis Clinical Research | Columbus | Ohio | 43215 | — |
| Aventiv Research | Dublin | Ohio | 43106 | — |
| OK Clinical Research, LLC | Edmond | Oklahoma | 73034 | — |
| Velocity Clinical Research, Medford (Crisor, LLC) | Medford | Oregon | 97504 | — |
| Safe Harbor Clinical Research | East Providence | Rhode Island | 02914 | — |
| VitaLink Research Anderson | Anderson | South Carolina | 29621 | — |
| Lowcountry Lung and Critical Care, P.A. | Charleston | South Carolina | 29406 | — |
| VitaLink Research Columbia | Columbia | South Carolina | 29204 | — |
| Piedmont Research Partners | Fort Mill | South Carolina | 29707 | — |
| VitaLink Research Gaffney | Gaffney | South Carolina | 29340 | — |
| VitaLink Research - Greenville | Greenville | South Carolina | 29615 | — |
| Clinical Research of Rock Hill | Rock Hill | South Carolina | 29732 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| VitaLink Research Spartanburg | Spartanburg | South Carolina | 29303 | — |
| CU Pharmaceutical Research | Union | South Carolina | 29379 | — |
| MultiSpecialty Clinical Research, Inc. | Johnson City | Tennessee | 37601 | — |
| New Phase Research Development | Knoxville | Tennessee | 37909 | — |
| PnP Research | Amarillo | Texas | 79106 | — |
| TTS Research | Boerne | Texas | 78006 | — |
| Corsicana Medical Research, PLLC | Corsicana | Texas | 75110 | — |
| Houston Pulmonary and Sleep Allergy and Asthma Associates | Cypress | Texas | 77429 | — |
| Metroplex Pulmonary and Sleep Center | McKinney | Texas | 75069 | — |
| Diagnostics Research Group | San Antonio | Texas | 78229 | — |
| Element Research Group | San Antonio | Texas | 78258 | — |
| Sherman Clinical Research | Sherman | Texas | 75092 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 53 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04542057, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2023 · Synced Oct 31, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04542057 live on ClinicalTrials.gov.