A Study to Test if TEV-48574 is Effective in Relieving Asthma
Public ClinicalTrials.gov record NCT04545385. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 16-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Proof-of-Concept Study to Evaluate the Efficacy and Safety of TEV-48574 in Adults With T2-low/Non-T2 Severe Uncontrolled Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study is to evaluate the effect of TEV-48574 compared with placebo on loss of asthma control (LoAC) in adult participants with T2-low and non-T2 severe asthma uncontrolled on inhaled corticosteroids plus long-acting beta-agonists (ICS+LABA). The secondary efficacy objective is to evaluate the effect of TEV-48574 compared with placebo on a range of clinical measures of asthma control. The duration of participant participation in the study is planned to be up to approximately 30 weeks.
Study identification
- NCT ID
- NCT04545385
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 65 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 7, 2020 (Actual)
- Primary completion
- Jan 17, 2022 (Actual)
- Completion
- Jan 17, 2022 (Actual)
- Last update posted
- Mar 13, 2023
2020 – 2022
United States locations
- U.S. sites
- 55
- U.S. states
- 21
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Teva Investigational Site 14884 | Birmingham | Alabama | 35209 | — |
| Teva Investigational Site 14915 | Little Rock | Arkansas | 72205 | — |
| Teva Investigational Site 14914 | Bakersfield | California | 93301 | — |
| Teva Investigational Site 15234 | Huntington Beach | California | 92647 | — |
| Teva Investigational Site 14896 | Los Angeles | California | 90025 | — |
| Teva Investigational Site 14918 | Los Angeles | California | 90025 | — |
| Teva Investigational Site 14913 | Los Angeles | California | 90048 | — |
| Teva Investigational Site 14910 | Rolling Hills Estates | California | 90274-7604 | — |
| Teva Investigational Site 14907 | San Diego | California | 92123 | — |
| Teva Investigational Site 14891 | San Jose | California | 95117 | — |
| Teva Investigational Site 15231 | Stockton | California | 95207 | — |
| Teva Investigational Site 14916 | Walnut Creek | California | 94598 | — |
| Teva Investigational Site 14878 | Westminster | California | 92683 | — |
| Teva Investigational Site 14895 | Colorado Springs | Colorado | 80907 | — |
| Teva Investigational Site 14917 | Denver | Colorado | 80246 | — |
| Teva Investigational Site 15222 | Coral Gables | Florida | 33134 | — |
| Teva Investigational Site 15223 | Cutler Bay | Florida | 33189 | — |
| Teva Investigational Site 14911 | Hialeah | Florida | 33012 | — |
| Teva Investigational Site 15225 | Hialeah | Florida | 33015 | — |
| Teva Investigational Site 14900 | Miami | Florida | 33134 | — |
| Teva Investigational Site 14883 | Miami | Florida | 33173 | — |
| Teva Investigational Site 14908 | Panama City | Florida | 32405 | — |
| Teva Investigational Site 14894 | Tallahassee | Florida | 32308-4355 | — |
| Teva Investigational Site 15224 | Tampa | Florida | 33607 | — |
| Teva Investigational Site 14924 | Evansville | Indiana | 47713 | — |
| Teva Investigational Site 14897 | Kansas City | Kansas | 66160 | — |
| Teva Investigational Site 15220 | Baltimore | Maryland | 21236 | — |
| Teva Investigational Site 14877 | North Dartmouth | Massachusetts | 02747-3322 | — |
| Teva Investigational Site 14922 | St Louis | Missouri | 63110 | — |
| Teva Investigational Site 14893 | St Louis | Missouri | 63141 | — |
| Teva Investigational Site 14904 | Missoula | Montana | 59808 | — |
| Teva Investigational Site 14912 | Bellevue | Nebraska | 68123-4303 | — |
| Teva Investigational Site 14903 | Lincoln | Nebraska | 68505-2343 | — |
| Teva Investigational Site 15227 | Skillman | New Jersey | 08558 | — |
| Teva Investigational Site 15221 | Charlotte | North Carolina | 28277 | — |
| Teva Investigational Site 15226 | Monroe | North Carolina | 28112 | — |
| Teva Investigational Site 14882 | Raleigh | North Carolina | 27607 | — |
| Teva Investigational Site 14887 | Wilmington | North Carolina | 28401 | — |
| Teva Investigational Site 14889 | Cincinnati | Ohio | 45231 | — |
| Teva Investigational Site 14886 | Dublin | Ohio | 43016 | — |
| Teva Investigational Site 14901 | Toledo | Ohio | 43617 | — |
| Teva Investigational Site 14888 | Edmond | Oklahoma | 73034 | — |
| Teva Investigational Site 14880 | Oklahoma City | Oklahoma | 73112-4432 | — |
| Teva Investigational Site 14923 | Philadelphia | Pennsylvania | 19140 | — |
| Teva Investigational Site 14890 | Charleston | South Carolina | 29406 | — |
| Teva Investigational Site 14925 | Allen | Texas | 75013 | — |
| Teva Investigational Site 15230 | Austin | Texas | 78759 | — |
| Teva Investigational Site 14909 | Dallas | Texas | 75231 | — |
| Teva Investigational Site 14902 | El Paso | Texas | 79903-3508 | — |
| Teva Investigational Site 14919 | Fort Worth | Texas | 76244 | — |
| Teva Investigational Site 14921 | Houston | Texas | 77030 | — |
| Teva Investigational Site 14905 | McKinney | Texas | 75069 | — |
| Teva Investigational Site 14879 | San Antonio | Texas | 78229 | — |
| Teva Investigational Site 14920 | Spokane | Washington | 99204 | — |
| Teva Investigational Site 14881 | Greenfield | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04545385, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 13, 2023 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04545385 live on ClinicalTrials.gov.