Trial of Therapeutic Hypothermia in Patients With ARDS
Public ClinicalTrials.gov record NCT04545424. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Cooling to Help Injured Lungs (CHILL) Phase IIB Randomized Control Trial of Therapeutic Hypothermia in Patients With ARDS
Study identification
- NCT ID
- NCT04545424
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Enrollment
- 340 participants
Conditions and interventions
Conditions
Interventions
- Hypothermia Device
- Neuromuscular Blocking Agents Drug
- Standard of care Device
Device · Drug
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 28, 2021
- Primary completion
- Aug 30, 2026
- Completion
- Oct 30, 2026
- Last update posted
- Nov 9, 2025
2021 – 2026
United States locations
- U.S. sites
- 19
- U.S. states
- 14
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | Not yet recruiting |
| Yale University | New Haven | Connecticut | 06520 | Terminated |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Rush University Medical Center | Chicago | Illinois | 60612 | Recruiting |
| Loyola University Chicago | Chicago | Illinois | 60660 | Terminated |
| University of Kentucky | Lexington | Kentucky | 40536 | Not yet recruiting |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | Recruiting |
| Johns Hopkins Hospital | Baltimore | Maryland | 21205 | Terminated |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Recruiting |
| Cooper Health System | Camden | New Jersey | 08103 | Recruiting |
| University of Cincinnati | Cincinnati | Ohio | 45219 | Recruiting |
| Cleveland Clinc | Cleveland | Ohio | 44195 | Recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| University of Pennsylavia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Temple University | Philadelphia | Pennsylvania | 19140 | Recruiting |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | Terminated |
| Intermountain Healthcare (Utah) | Salt Lake City | Utah | 84132 | Recruiting |
| University of Wisconsin | Madison | Wisconsin | 53792 | Terminated |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04545424, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 9, 2025 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04545424 live on ClinicalTrials.gov.