Pivotal Study to Evaluate Safety and Immunogenicity of a Live-Attenuated Chikungunya Virus Vaccine Candidate in Adults
Public ClinicalTrials.gov record NCT04546724. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Placebo-Controlled, Double-Blinded Pivotal Study To Evaluate Safety And Immunogenicity Of A Live-Attenuated Chikungunya Virus Vaccine Candidate In Adults Aged 18 Years And Above
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This was a prospective, randomized, double-blinded, multicenter, pivotal clinical study evaluating the final dose of VLA1553 (1 x10E4 TCID50 per dose) in comparison to a placebo control. The final dose of VLA1553 or control was administered as single immunization on Day 1. Overall, 4.128 male and female subjects aged 18 years and above were randomized into the study.
Study identification
- NCT ID
- NCT04546724
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 4,128 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 17, 2020 (Actual)
- Primary completion
- May 19, 2021 (Actual)
- Completion
- Oct 15, 2021 (Actual)
- Last update posted
- Jun 28, 2023
2020 – 2021
United States locations
- U.S. sites
- 44
- U.S. states
- 22
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Accelerated Enrollment Solutions (AES) | Chandler | Arizona | 85224 | — |
| Accelerated Enrollment Solutions (AES) | Phoenix | Arizona | 85020 | — |
| Alliance for Multispecialty Research (AMR) | Tempe | Arizona | 85283 | — |
| ELITE Research Network (ELITE) | Little Rock | Arkansas | 72204 | — |
| Velocity Clinical Research, Chula Vista | Chula Vista | California | 91911 | — |
| Accelerated Enrollment Solutions (AES) | San Diego | California | 92108 | — |
| Accel Research Sites - DeLand | DeLand | Florida | 32720 | — |
| ELITE Research Network (ELITE) | Hallandale | Florida | 33009 | — |
| Meridien Research - Maitland | Maitland | Florida | 32751 | — |
| Accelerated Enrollment Solutions (AES) | Melbourne | Florida | 32934 | — |
| Suncoast Research Group, LLC | Miami | Florida | 33135 | — |
| ELITE Research Network (ELITE) | North Miami Beach | Florida | 33135 | — |
| Jacksonville Center for Clinical Research, LTD dba St. Johns Center for Clinical Research | Ponte Vedra | Florida | 32081 | — |
| Synexus - The Villages | The Villages | Florida | 32162 | — |
| ELITE Research Network (ELITE) | Meridian | Idaho | 83642 | — |
| Accelerated Enrollment Solutions (AES) | Chicago | Illinois | 60602 | — |
| Accelerated Enrollment Solutions (AES) | Peoria | Illinois | 61614 | — |
| Alliance for Multispecialty Research (AMR) | El Dorado | Kansas | 67042 | — |
| Alliance for Multispecialty Research (AMR) | Newton | Kansas | 67114 | — |
| Alliance for Multispecialty Research (AMR) | Wichita | Kansas | 67207 | — |
| Alliance for Multispecialty Research (AMR) | Lexington | Kentucky | 40509 | — |
| AMR - New Orleans - Center for Clinical Research | New Orleans | Louisiana | 70119 | — |
| Alliance for Multispecialty Research (AMR) | Kansas City | Missouri | 64114 | — |
| Meridian Clinical Research - Grand Island | Grand Island | Nebraska | 68803 | — |
| Platinum Research Network (Platinum) | Omaha | Nebraska | 68134 | — |
| Accelerated Enrollment Solutions (AES) | Omaha | Nebraska | 68144 | — |
| Alliance for Multispecialty Research (AMR) | Las Vegas | Nevada | 89119 | — |
| Meridian Clinical Research | Endwell | New York | 13760 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Lucas Research | Morehead City | North Carolina | 28557 | — |
| ELITE Research Network (ELITE) | Wilmington | North Carolina | 28403 | — |
| Accelerated Enrollment Solutions (AES) | Cincinnati | Ohio | 45236 | — |
| ELITE Research Network (ELITE) | Oklahoma City | Oklahoma | 73112 | — |
| Velocity Clinical Research - Medford | Medford | Oregon | 97504 | — |
| Synexus - Anderson | Anderson | South Carolina | 29621 | — |
| Vitalink Research - Anderson | Anderson | South Carolina | 29621 | — |
| Alliance for Multispecialty Research (AMR) | Knoxville | Tennessee | 37920 | — |
| Tekton Research - Beaumont | Beaumont | Texas | 77706 | — |
| PanAmerican Clinical Research - US Headquarter | Brownsville | Texas | 78521 | — |
| Velocity Clinical Research - Austin | Cedar Park | Texas | 78613 | — |
| Research Your Health, LLC | Plano | Texas | 75093 | — |
| ELITE Research Network (ELITE) | Tomball | Texas | 77375 | — |
| ELITE Research Network (ELITE) | West Jordan | Utah | 84088 | — |
| Alliance for Multispecialty Research (AMR) | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04546724, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 28, 2023 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04546724 live on ClinicalTrials.gov.