Target Engagement of Terazosin in Healthy Adults

ClinicalTrials.gov ID: NCT04551040

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Official title

Assessing Target Engagement of Terazosin in Healthy Adults

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to assess the target engagement of Terazosin (TZ) in a single cohort of 6 healthy adult participants. During the study participants will undergo PET/CT scans, 7-Tesla MRI scans, blood draws, and an optional lumbar puncture (LP.)

Study identification

NCT ID: NCT04551040
Recruitment status: Active, not recruiting
Study type: Interventional
Phase: Phase 1
Lead sponsor: University of Iowa; Other
Enrollment: 18 participants

Conditions and interventions

Conditions

Healthy

Interventions

Terazosin Drug

Drug

Eligibility (public fields only)

Age range: 60 Years to 90 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 26, 2021 (Actual)
Primary completion: Mar 1, 2023 (Actual)
Completion: Jun 30, 2025 (Estimated)
Last update posted: Jan 14, 2025

2021 – 2025

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Iowa Hospitals and Clinics	Iowa City	Iowa	52242	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04551040, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 14, 2025 · Synced Nov 14, 2026