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Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Natural Versus Programmed Frozen Embryo Transfer (NatPro)

ClinicalTrials.gov ID: NCT04551807

Public ClinicalTrials.gov record NCT04551807. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 18, 2026, 10:14 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Multi-center, Parallel-group, Randomized Controlled Trial of Modified Natural Versus Programmed Cycles for Frozen Embryo Transfers and Their Association With Preeclampsia and Live Births

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum absent).

Study identification

NCT ID
NCT04551807
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Enrollment
788 participants

Conditions and interventions

Interventions

Procedure

Eligibility (public fields only)

Age range
18 Years to 41 Years
Sex
Female
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 16, 2020 (Actual)
Primary completion
Feb 1, 2026 (Estimated)
Completion
Apr 1, 2026 (Estimated)
Last update posted
May 16, 2025

2020 – 2026

United States locations

U.S. sites
15
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
University of California San Francisco San Francisco California 94158 —
Stanford University Sunnyvale California 94087 —
Yale Orange Connecticut 06477 —
Fertility Institute of Hawaii Honolulu Hawaii 96814 —
Northwestern University Chicago Illinois 60611 —
Johns Hopkins Baltimore Maryland 21093 —
Shady Grove Fertility Rockville Maryland 20850 —
Boston IVF Waltham Massachusetts 02451 —
University of Rochester Rochester New York 14642 —
Atrium Health Charlotte North Carolina 28203 —
Cleveland Clinic Foundation Beachwood Ohio 44122 —
University of Oklahoma Oklahoma City Oklahoma 73104 —
University of Pennsylvania Philadelphia Pennsylvania 19104 —
CARE Fertility Bedford Texas 76022 —
West Virginia University Center for Reproductive Medicine Morgantown West Virginia 26505 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04551807, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 16, 2025 · Synced Oct 18, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04551807 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →