ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov ID: NCT04552899
Public ClinicalTrials.gov record NCT04552899. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase III study will evaluate the efficacy, safety and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) zinpentraxin alfa, compared with placebo in participants with idiopathic pulmonary fibrosis (IPF).
Study identification
- NCT ID
- NCT04552899
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 665 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 18, 2021
- Primary completion
- Feb 9, 2023
- Completion
- Feb 9, 2023
- Last update posted
- Apr 17, 2024
2021 – 2023
United States locations
- U.S. sites
- 72
- U.S. states
- 30
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Banner University Medical Center Phoenix; Main Pharmacy | Phoenix | Arizona | 85006 | — |
| Lovelace Scientific Resources, Inc. | Phoenix | Arizona | 85016 | — |
| UC Irvine Medical Center | Orange | California | 92868 | — |
| Stanford Hospital and Clinics | Palo Alto | California | 94304 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| Inst. of Healthcare Assessment, Inc. | San Diego | California | 92120 | — |
| UCSF Medical Center | San Francisco | California | 94143-0748 | — |
| Paloma Medical Group | San Juan Capistrano | California | 92675 | — |
| William Sansum Diabetes Center | Santa Barbara | California | 93105 | — |
| University of Colorado - Anschutz Medical Campus (University of Colorado Health Sciences Center) | Aurora | Colorado | 80045 | — |
| National Jewish Health Medical Center | Denver | Colorado | 80045-2541 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Meris Clinical Research | Brandon | Florida | 33511-5719 | — |
| Florida Lung, Asthma and Sleep Specialists (FLASS) - Celebration | Celebration | Florida | 34747-1818 | — |
| Advanced Pulmonary & Sleep Research Institute of Florida | Daytona Beach | Florida | 32117 | — |
| University of Florida Division of Pulmonary, Critical Care, and Sleep Medicine | Gainesville | Florida | 32608-3928 | — |
| Malcom Randall VA Medical Center | Gainesville | Florida | 32608 | — |
| University of Florida Health Pulmonology - Jacksonville | Jacksonville | Florida | 32209 | — |
| Advanced Pulmonary Research Institute | Loxahatchee Groves | Florida | 33470-9216 | — |
| San Marcus Research Clinic Inc. | Miami | Florida | 33014 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Central Florida Pulmonary Group, PA | Orlando | Florida | 32803 | — |
| Sarasota Memorial Health Care System; Cancer Research Program | Sarasota | Florida | 34239 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Integral ? Clinical Trial Solutions | Weston | Florida | 33327 | — |
| Clinical Site Partners Orlando | Winter Park | Florida | 32789 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Piedmont Healthcare Pulmonary and Critical Care Research | Austell | Georgia | 30106 | — |
| NorthShore University HealthSystem | Evanston | Illinois | 60201 | — |
| Indiana Univ School of Med | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals and Clinics; Investigational Drug Services | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Louisville Health Sciences Center | Louisville | Kentucky | 40202 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham & Women'S Hospital | Boston | Massachusetts | 02115 | — |
| Covenant Medical Center - Cooper | Saginaw | Michigan | 48602-5383 | — |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 29425-8911 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55902 | — |
| The Lung Research Center | Chesterfield | Missouri | 63017-3625 | — |
| Washington University | St Louis | Missouri | 63128 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-0600 | — |
| Pulmonary & Allergy Associates | Summit | New Jersey | 07901-4055 | — |
| Lenox Hill Hospital | New York | New York | 10075 | — |
| American Health Research Inc. | Charlotte | North Carolina | 28277 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Pulmonix Research | Greensboro | North Carolina | 27403-1127 | — |
| PMG Research of Wilmington | Wilmington | North Carolina | 28401 | — |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45219 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Mercy St. Vincent Medical Center | Toledo | Ohio | 43608 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Jefferson University Physicians (JUP) - Jefferson Pulmonary | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Medical Center | Philadelphia | Pennsylvania | 19140-4105 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina Hospital | Charleston | South Carolina | 29425 | — |
| SleepMed of South Carolina | Columbia | South Carolina | 29201-2953 | — |
| Lowcountry Lung and Critical Care | North Charleston | South Carolina | 29406 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| Horizon Clinical Research Group | Cypress | Texas | 77429 | — |
| Cardiopulmonary Research Science and Technology Institute | Dallas | Texas | 75230 | — |
| University of Texas Southwestern Medical Center; Heart and Lung Clinic | Dallas | Texas | 75390-8575 | — |
| University of Texas Medical Branch; Cardiology Department | Galveston | Texas | 77555 | — |
| DCOL Center for Clinical Research | Longview | Texas | 75605-2410 | — |
| Metroplex Pulmonology & Sleep Center | McKinney | Texas | 75069 | — |
| Audie L. Murphy VA Hospital, STVHCS | San Antonio | Texas | 78229 | — |
| University Of Utah Hosp & Clin; Investigational Pharmacy | Salt Lake City | Utah | 84132 | — |
| Inova Fairfax Hospital/IHVI; Cardiology | Falls Church | Virginia | 22042 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23219-1901 | — |
| University of Wisconsin-Madison | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 288 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04552899, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 17, 2024 · Synced Sep 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04552899 live on ClinicalTrials.gov.