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Terminated Phase 2 Interventional Results available

Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease

ClinicalTrials.gov ID: NCT04553406

Public ClinicalTrials.gov record NCT04553406. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 7:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Partially Blinded, Placebo- and Comparator-Controlled, Multicenter, Phase 2a, Dose Ranging, Proof-of-Concept Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of SPR720 as Compared With Placebo or Standard of Care for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Study identification

NCT ID
NCT04553406
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Spero Therapeutics
Industry
Enrollment
2 participants

Conditions and interventions

Interventions

  • SPR720 Drug
  • Placebo Drug
  • Open-label Standard of Care Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2, 2020
Primary completion
Jan 27, 2021
Completion
Jan 27, 2021
Last update posted
Feb 27, 2022

2020 – 2021

United States locations

U.S. sites
9
U.S. states
3
U.S. cities
9
Facility City State ZIP Site status
Medical Facility Altamonte Springs Florida 32701
Medical Facility Atlantis Florida 33462
Medical Facility Clearwater Florida 33765
Medical Facility Kissimmee Florida 34746
Medical Facility West Palm Beach Florida 33407
Medical Facility Charlotte North Carolina 28207
Medical Facility Mooresville North Carolina 28117
Medical Facility Winston-Salem North Carolina 27103
Medical Facility Pittsburgh Pennsylvania 15213

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04553406, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 27, 2022 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04553406 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →