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Completed Phase 3 Interventional Results available

PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD

ClinicalTrials.gov ID: NCT04556656

Public ClinicalTrials.gov record NCT04556656. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 1:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Arm, Multicenter Study Evaluating the Efficacy and Safety of Pridopidine in Patients With Early Stage of Huntington Disease

Study identification

NCT ID
NCT04556656
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Prilenia
Industry
Enrollment
499 participants

Conditions and interventions

Interventions

  • Pridopidine Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
25 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 15, 2020
Primary completion
Mar 13, 2023
Completion
Mar 20, 2024
Last update posted
Mar 11, 2025

2020 – 2024

United States locations

U.S. sites
26
U.S. states
20
U.S. cities
25
Facility City State ZIP Site status
Prilenia Investigational Site (Site 061) Davis California 95616
Prilenia Investigational Site (Site 051) San Diego California 92093
Prilenia Investigational Site (Site 343) Englewood Colorado 80113
Prilenia Investigational Site (Site 333) Washington D.C. District of Columbia 20057
Prilenia Investigational Site (Site 160) Gainesville Florida 32611
Prilenia Investigational Site (Site 019) Tampa Florida 33620
Prilenia Investigational Site (Site 032) Atlanta Georgia 30322
Prilenia Investigational Site (Site 088) Chicago Illinois 60611
Prilenia Investigational Site (Site 029) Kansas City Kansas 66103
Prilenia Investigational Site (Site 083) Wichita Kansas 67226
Prilenia Investigational Site (Site 087) Louisville Kentucky 40292
Prilenia Investigational Site (Site 028) Baltimore Maryland 21218
Prilenia Investigational Site (Site 017) Boston Massachusetts 02114
Prilenia Investigational Site (Site 076) Boston Massachusetts 02215
Prilenia Investigational Site (Site 027) St Louis Missouri 63130
Prilenia Investigational Site (Site 037) Albany New York 12208
Prilenia Investigational Site (Site 002) New York New York 10027
Prilenia Investigational Site (Site 119) Durham North Carolina 27708
Prilenia Investigational Site (Site 089) Cincinnati Ohio 45221
Prilenia Investigational Site (Site 020) Columbus Ohio 43210
Prilenia Investigational Site (Site 006) Portland Oregon 97239
Prilenia Investigational Site (Site 018) Philadelphia Pennsylvania 19104
Prilenia Investigational Site (Site 031) Nashville Tennessee 37232
Prilenia Investigational Site (Site 199) Houston Texas 77004
Prilenia Investigational Site (Site 326) Richmond Virginia 23284
Prilenia Investigational Site (Site 096) Seattle Washington 98195

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04556656, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 11, 2025 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04556656 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →