PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD
Public ClinicalTrials.gov record NCT04556656. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Arm, Multicenter Study Evaluating the Efficacy and Safety of Pridopidine in Patients With Early Stage of Huntington Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy and safety of pridopidine 45mg twice daily (BID) in patients with early stage manifest Huntington Disease (HD).
Study identification
- NCT ID
- NCT04556656
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 499 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 25 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 16, 2020 (Actual)
- Primary completion
- Mar 14, 2023 (Actual)
- Completion
- Mar 21, 2024 (Actual)
- Last update posted
- Mar 12, 2025
2020 – 2024
United States locations
- U.S. sites
- 26
- U.S. states
- 20
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Prilenia Investigational Site (Site 061) | Davis | California | 95616 | — |
| Prilenia Investigational Site (Site 051) | San Diego | California | 92093 | — |
| Prilenia Investigational Site (Site 343) | Englewood | Colorado | 80113 | — |
| Prilenia Investigational Site (Site 333) | Washington D.C. | District of Columbia | 20057 | — |
| Prilenia Investigational Site (Site 160) | Gainesville | Florida | 32611 | — |
| Prilenia Investigational Site (Site 019) | Tampa | Florida | 33620 | — |
| Prilenia Investigational Site (Site 032) | Atlanta | Georgia | 30322 | — |
| Prilenia Investigational Site (Site 088) | Chicago | Illinois | 60611 | — |
| Prilenia Investigational Site (Site 029) | Kansas City | Kansas | 66103 | — |
| Prilenia Investigational Site (Site 083) | Wichita | Kansas | 67226 | — |
| Prilenia Investigational Site (Site 087) | Louisville | Kentucky | 40292 | — |
| Prilenia Investigational Site (Site 028) | Baltimore | Maryland | 21218 | — |
| Prilenia Investigational Site (Site 017) | Boston | Massachusetts | 02114 | — |
| Prilenia Investigational Site (Site 076) | Boston | Massachusetts | 02215 | — |
| Prilenia Investigational Site (Site 027) | St Louis | Missouri | 63130 | — |
| Prilenia Investigational Site (Site 037) | Albany | New York | 12208 | — |
| Prilenia Investigational Site (Site 002) | New York | New York | 10027 | — |
| Prilenia Investigational Site (Site 119) | Durham | North Carolina | 27708 | — |
| Prilenia Investigational Site (Site 089) | Cincinnati | Ohio | 45221 | — |
| Prilenia Investigational Site (Site 020) | Columbus | Ohio | 43210 | — |
| Prilenia Investigational Site (Site 006) | Portland | Oregon | 97239 | — |
| Prilenia Investigational Site (Site 018) | Philadelphia | Pennsylvania | 19104 | — |
| Prilenia Investigational Site (Site 031) | Nashville | Tennessee | 37232 | — |
| Prilenia Investigational Site (Site 199) | Houston | Texas | 77004 | — |
| Prilenia Investigational Site (Site 326) | Richmond | Virginia | 23284 | — |
| Prilenia Investigational Site (Site 096) | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04556656, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 12, 2025 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04556656 live on ClinicalTrials.gov.