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Completed Phase 2 Interventional Results available

Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata

ClinicalTrials.gov ID: NCT04556734

Public ClinicalTrials.gov record NCT04556734. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 10:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, 24-Week Study, With a 28-Week Open-Label Extension, to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Alopecia Areata

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety and efficacy of etrasimod monotherapy (2 milligrams \[mg\] and 3 mg) in participants with moderate-to-severe alopecia areata (AA).

Study identification

NCT ID
NCT04556734
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
80 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 28, 2020
Primary completion
Jun 6, 2023
Completion
Jun 6, 2023
Last update posted
Jun 25, 2024

2020 – 2023

United States locations

U.S. sites
39
U.S. states
18
U.S. cities
27
Facility City State ZIP Site status
Investigate MD Scottsdale Arizona 85255
Dermatology Trial Associates Bryant Arkansas 72022
California Dermatology & Clinical Research Institute Encinitas California 92024
First OC Dermatology Fountain Valley California 92708
University of California,Irvine Irvine California 92697
Prospect Optometry Lomita California 90717
Torrance Clinical Research Institute,Inc. Lomita California 90717
Yale Eye Center New Haven Connecticut 06511
Yale Investigational Drug Services New Haven Connecticut 06511
Yale Center for Clinical Investigation New Haven Connecticut 06519
Yale New Haven Hospital Department of Respiratory Care New Haven Connecticut 06519
Advanced Sleep & Respiratory Institute, PA Daytona Beach Florida 32117
International Eye Associates Ormond Beach Florida 32174
Leavitt Medical Associates of Florida d/ba Ameriderm Research Ormond Beach Florida 32174
Advanced Clinical Research Institute Tampa Florida 33607
Advanced Medical Research PC Sandy Springs Georgia 30328
Dawes Fretzin Clinical Research Group, LLC Indianapolis Indiana 46250
Eye Surgeons of Indiana Indianapolis Indiana 46260
Magnante Eye Care (Ophthalmological Assessments) Lafayette Indiana 47905
Physicians Research Group (Administrative Office Location) Noblesville Indiana 46060
Physicians Research Group West Lafayette Indiana 47906
Randall Dermatology, PC West Lafayette Indiana 47906
Lawrence J. Green, MD LLC Rockville Maryland 20850
Michigan Center for Skin Care Research Clinton Township Michigan 48038
MediSearch Clinical Trials Saint Joseph Missouri 64506
NYC Retina- Manhattan New York New York 10003
Bobby Buka MD, PC New York New York 10012
Rochester Ophthalmological Group Rochester New York 14623
Skin Search of Rochester, Inc. Rochester New York 14623
WDC Cosmetic and Research, PLLC Wilmington North Carolina 28405
NW Dermatology Institute Portland Oregon 97210
UPMC Department of Dermatology Pittsburgh Pennsylvania 15213
UPMC Eye Center Pittsburgh Pennsylvania 15213
International Clinical Research - Tennessee LLC Murfreesboro Tennessee 37130
Progressive Clinical Research, PA San Antonio Texas 78213
The Education & Research Foundation, Inc. Lynchburg Virginia 24501
Dermatology Specialists of Spokane Spokane Washington 99202
PRINCIPLE RESEARCH SOLUTIONS (pulmonary function testing) Spokane Washington 99204
SPOKANE EYE CLINIC (OCT and optical exam Spokane Washington 99204

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04556734, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 25, 2024 · Synced Sep 3, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04556734 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →