Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial

ClinicalTrials.gov ID: NCT04565119

Open the official record

This page only displays public information reproduced from the official ClinicalTrials.gov record NCT04565119. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:53 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial (BioBOOST)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

BioBOOST is a multicenter, observational study of the effect of derangements in brain physiologic parameters on brain injury biomarker levels in patients with severe traumatic brain injury.

Study identification

NCT ID: NCT04565119
Recruitment status: Active, not recruiting
Study type: Observational
Phase: Not listed
Lead sponsor: University of Pennsylvania; Other
Enrollment: 300 participants

Conditions and interventions

Conditions

TBI (Traumatic Brain Injury)

Interventions

No intervention. This is an observational study. Other

Other

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 20, 2020 (Actual)
Primary completion: Dec 31, 2026 (Estimated)
Completion: Dec 31, 2027 (Estimated)
Last update posted: May 6, 2026

2020 – 2027

United States locations

U.S. sites: 2
U.S. states: 2
U.S. cities: 2

Facility	City	State	ZIP	Site status
University of Michigan	Ann Arbor	Michigan	48109	—
Penn Presbyterian Medical Center	Philadelphia	Pennsylvania	19104	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04565119, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 6, 2026 · Synced Nov 14, 2026