Efficacy and Safety of Molnupiravir (MK-4482) in Hospitalized Adult Participants With COVID-19 (MK-4482-001)
Public ClinicalTrials.gov record NCT04575584. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3, Randomized, Placebo-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of MK-4482 in Hospitalized Adults With COVID-19
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study aims to evaluate the safety, tolerability and efficacy of molnupiravir (MK-4482) compared to placebo. The primary hypothesis is that molnupiravir is superior to placebo as assessed by the rate of sustained recovery through Day 29.
Study identification
- NCT ID
- NCT04575584
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 304 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 19, 2020 (Actual)
- Primary completion
- Aug 11, 2021 (Actual)
- Completion
- Aug 11, 2021 (Actual)
- Last update posted
- Jan 17, 2023
2020 – 2021
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Foundation Hospital - South Bay ( Site 1832) | Harbor City | California | 90710 | — |
| Cedars-Sinai Medical Center ( Site 1822) | Los Angeles | California | 90048 | — |
| University of California Davis Health ( Site 1809) | Sacramento | California | 95817 | — |
| University Of Florida ( Site 1810) | Gainesville | Florida | 32610 | — |
| Wellstar Kennestone Hospital ( Site 1801) | Marietta | Georgia | 30060 | — |
| Loretto Hospital ( Site 1838) | Chicago | Illinois | 60644 | — |
| LSU-HSC Shreveport ( Site 1824) | Shreveport | Louisiana | 71103 | — |
| Henry Ford Health System ( Site 1821) | Detroit | Michigan | 48202-2608 | — |
| University of Mississippi Medical Center ( Site 1846) | Jackson | Mississippi | 39216 | — |
| University of Nebraska Medical Center ( Site 1835) | Omaha | Nebraska | 68198 | — |
| University of New Mexico, Health Sciences Center ( Site 1806) | Albuquerque | New Mexico | 87131 | — |
| Carolinas Medical Center ( Site 1850) | Charlotte | North Carolina | 28203 | — |
| ECU Adult Specialty Care ( Site 1865) | Greenville | North Carolina | 27834 | — |
| Sanford Health ( Site 1851) | Fargo | North Dakota | 58122 | — |
| Temple University ( Site 1836) | Philadelphia | Pennsylvania | 19140 | — |
| CHRISTUS Institute for Innovation & Advanced Clinical Care ( Site 1864) | Corpus Christi | Texas | 78404 | — |
| Houston Methodist Hospital ( Site 1863) | Houston | Texas | 77030 | — |
| Swedish Medical Center ( Site 1812) | Edmonds | Washington | 98026 | — |
| Valley Medical Center ( Site 1815) | Renton | Washington | 98055 | — |
| Swedish Medical Center ( Site 1861) | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 69 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04575584, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 17, 2023 · Synced Oct 31, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04575584 live on ClinicalTrials.gov.