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Active, not recruiting Phase 2 Interventional

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

ClinicalTrials.gov ID: NCT04576104

Public ClinicalTrials.gov record NCT04576104. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Surgical Window of Opportunity Study of Megestrol Acetate Compared With Megestrol Acetate and Metformin for Endometrial Intraepithelial Neoplasia

Study identification

NCT ID
NCT04576104
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Northwestern University
Other
Enrollment
51 participants

Conditions and interventions

Interventions

  • Biopsy Procedure Procedure
  • Extended Release Metformin Hydrochloride Drug
  • Megestrol Acetate Drug
  • Questionnaire Administration Other

Procedure · Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 28, 2021
Primary completion
Aug 27, 2025
Completion
Jun 29, 2026
Last update posted
Jan 20, 2026

2021 – 2026

United States locations

U.S. sites
8
U.S. states
6
U.S. cities
8
Facility City State ZIP Site status
Cedars Sinai Medical Center Los Angeles California 90048
University of Colorado Denver Colorado 80217-3364
Northwestern University Chicago Illinois 60611
Northwestern Medicine Central DuPage Hospital Winfield Illinois 60190
Dana-Farber Cancer Institute Boston Massachusetts 02215
University of Minnesota/Masonic Cancer Center Minneapolis Minnesota 55455
UNC Lineberger Comprehensive Cancer Center Chapel Hill North Carolina 27599
Duke University Medical Center Durham North Carolina 27710

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04576104, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 20, 2026 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04576104 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →