A Study of Cytisinicline for Smoking Cessation in Adult Smokers
Public ClinicalTrials.gov record NCT04576949. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-blind, Randomized, Placebo-controlled Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline in Adult Smokers
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This placebo-controlled Phase 3 study is being conducted at sites within the United States to evaluate 3 mg cytisinicline 3 times daily (TID) for treatment duration of 42 days/6 weeks and evaluate 3 mg cytisinicline TID for treatment duration of 84 days/12 weeks.
Study identification
- NCT ID
- NCT04576949
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 810 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 13, 2020 (Actual)
- Primary completion
- Dec 23, 2021 (Actual)
- Completion
- Dec 23, 2021 (Actual)
- Last update posted
- Jan 15, 2026
2020 – 2021
United States locations
- U.S. sites
- 17
- U.S. states
- 17
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alliance for Multispecialty Research, LLC. | Mobile | Alabama | 36608 | — |
| Arizona State University | Phoenix | Arizona | 85044 | — |
| Alliance for Multispecialty Research, LLC | Coral Gables | Florida | 33134 | — |
| Clinical Research Atlanta | Atlanta | Georgia | 30281 | — |
| MediSphere Medical Research Center, LLC | Evansville | Indiana | 47714 | — |
| Alliance for Multispecialty Research, LLC | Wichita | Kansas | 67207 | — |
| AMR Lexington | Lexington | Kentucky | 40509 | — |
| Alliance for Multispecialty Research, LLC | New Orleans | Louisiana | 70119 | — |
| Massachusetts General Hospital - Clinical Genetic Research Facility | Boston | Massachusetts | 02114 | — |
| Alliance for Multispecialty Research, LLC | Kansas City | Missouri | 64114 | — |
| Alliance for Multispecialty Research, LLC | Las Vegas | Nevada | 89119 | — |
| Rochester Clinical Research, Inc. | Rochester | New York | 14609 | — |
| M3 Wake Research, Inc. | Raleigh | North Carolina | 27612 | — |
| Coastal Carolina Research Center, Inc. | Mt. Pleasant | South Carolina | 29464 | — |
| Alliance for Multispecialty Research, LLC. | Knoxville | Tennessee | 37920 | — |
| FutureSearch Trials of Dallas, LP | Dallas | Texas | 75231 | — |
| Alliance for Multispecialty Research, LLC | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04576949, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 15, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04576949 live on ClinicalTrials.gov.