Crossover Trial of AD109 in Obstructive Sleep Apnea
Public ClinicalTrials.gov record NCT04580394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2 Randomized Double-Blind Placebo-Controlled 4-Period Single-Dose Crossover Factorial Study to Evaluate the Contribution of the Individual Drug Components to the Efficacy of AD109 in Obstructive Sleep Apnea
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, 4-period, placebo-controlled, crossover, phase 2 clinical study to examine the efficacy and safety of AD109 versus its individual components or placebo in patients with obstructive sleep apnea.
Study identification
- NCT ID
- NCT04580394
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Interventions
- AD109 Drug
- Atomoxetine Drug
- R-oxybutynin Drug
- Placebo Drug
- Digit System Substitution Test Diagnostic Test
Drug · Diagnostic Test
Eligibility (public fields only)
- Age range
- 25 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 27, 2020 (Actual)
- Primary completion
- May 28, 2021 (Actual)
- Completion
- May 28, 2021 (Actual)
- Last update posted
- Jan 31, 2023
2020 – 2021
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Preferred Research Partners, Inc. | Little Rock | Arkansas | 72211 | — |
| Empire Clinical Research | Pomona | California | 91767 | — |
| Yale University | New Haven | Connecticut | 06511 | — |
| Teradan Clinical Trials | Brandon | Florida | 33511 | — |
| Clinical Trials of Florida | Miami | Florida | 33186 | — |
| The Neurological Center of North Georgia | Gainesville | Georgia | 30501 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04580394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 31, 2023 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04580394 live on ClinicalTrials.gov.