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Completed Phase 3 Interventional Results available

Metabolism Informed Smoking Treatment: The MIST RCT

ClinicalTrials.gov ID: NCT04590404

Public ClinicalTrials.gov record NCT04590404. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Metabolism Informed Smoking Treatment in Medicaid and Medicare Patients: The MIST RCT

Study identification

NCT ID
NCT04590404
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Enrollment
606 participants

Conditions and interventions

Conditions

Interventions

  • Post-discharge automated phone calls (IVR) with option to connect with a tobacco coach. Behavioral
  • Nicotine Replacement Therapy Drug
  • Varenicline Drug
  • Metabolism Informed Smoking Treatment (Nicotine metabolite ratio (NMR)-based selection of pharmacotherapy) Other

Behavioral · Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 16, 2020
Primary completion
May 19, 2024
Completion
Nov 21, 2024
Last update posted
Dec 4, 2025

2020 – 2024

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Vanderbilt University Medical Center ViTAL, Vanderbilt Center for Tobacco, Addiction, and Lifestyle General Internal Medicine and Public Health 2525 West End Ave, Suite 450 Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04590404, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 4, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04590404 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →