Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF
Public ClinicalTrials.gov record NCT04592380. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Parallel Group Controlled Comparison Study of Clevidipine Versus Placebo or Standard of Care for Dyspnea and Blood Pressure Control in Acute Heart Failure (PRONTO II)
Study identification
- NCT ID
- NCT04592380
- Recruitment status
- Withdrawn
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- The Medicines Company
- Industry
- Enrollment
- Not listed
Conditions and interventions
Conditions
Interventions
- Stage 1: Clevidipine (double-blinded) Drug
- Stage 1: Placebo (double-blinded) Drug
- Stage 2: Clevidipine (open-label) Drug
- Stage 2: Standard of Care (open-label) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2014
- Primary completion
- Jan 31, 2016
- Completion
- Oct 31, 2016
- Last update posted
- Oct 18, 2020
2014 – 2016
United States locations
- U.S. sites
- 9
- U.S. states
- 7
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Drug Research and Analysis Corporation/Jackson Hospital | Montgomery | Alabama | 36106 | — |
| University of Arizona Medical Center | Tucson | Arizona | 85719 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215 | — |
| Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| Stony Brook University and Medical Center | Stony Brook | New York | 11794 | — |
| Duke University Hospital | Durham | North Carolina | 27710 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04592380, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 18, 2020 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04592380 live on ClinicalTrials.gov.