A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis
Public ClinicalTrials.gov record NCT04594707. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Open-label Extension Study to Evaluate Long-term Safety and Efficacy of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaulate the long-term safety, efficacy and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) zinpentraxin alfa, administered by intravenous (IV) infusion to participants with idiopathic pulmonary fibrosis (IPF).
Study identification
- NCT ID
- NCT04594707
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 117 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2021 (Actual)
- Primary completion
- Feb 10, 2023 (Actual)
- Completion
- Feb 10, 2023 (Actual)
- Last update posted
- May 16, 2024
2021 – 2023
United States locations
- U.S. sites
- 40
- U.S. states
- 23
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| Inst. of Healthcare Assessment, Inc. | San Diego | California | 92120 | — |
| UCSF Medical Center | San Francisco | California | 94143-0748 | — |
| National Jewish Health Medical Center | Denver | Colorado | 80045-2541 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Meris Clinical Research | Brandon | Florida | 33511-5719 | — |
| Florida Lung, Asthma and Sleep Specialists (FLASS) - Celebration | Celebration | Florida | 34747-1818 | — |
| Advanced Pulmonary & Sleep Research Institute of Florida | Daytona Beach | Florida | 32117 | — |
| University of Florida Health Pulmonology - Jacksonville | Jacksonville | Florida | 32209 | — |
| Advanced Pulmonary Research Institute | Loxahatchee Groves | Florida | 33470-9216 | — |
| Sarasota County Public Hospital | Sarasota | Florida | 34239 | — |
| Renstar Medical Research | Wesley Chapel | Florida | 33544 | — |
| Florida Pulmonary Research Institute, LLC | Winter Park | Florida | 32789 | — |
| NorthShore University HealthSystem | Evanston | Illinois | 60201 | — |
| University of Iowa Hospitals and Clinics; Investigational Drug Services | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Louisville Health Sciences Center | Louisville | Kentucky | 40202 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 29425-8911 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55902 | — |
| The Lung Research Center | Chesterfield | Missouri | 63017-3625 | — |
| Washington University | St Louis | Missouri | 63128 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-0600 | — |
| Lenox Hill Hospital | New York | New York | 10075 | — |
| Pulmonix Research | Greensboro | North Carolina | 27403-1127 | — |
| PMG Research of Wilmington | Wilmington | North Carolina | 28401 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Jefferson University Physicians (JUP) - Jefferson Pulmonary | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| SleepMed of South Carolina | Columbia | South Carolina | 29201-2953 | — |
| Lowcountry Lung and Critical Care | North Charleston | South Carolina | 29406 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| University of Texas Medical Branch at Galveston | Galveston | Texas | 77555 | — |
| Metroplex Pulmonology & Sleep Center | McKinney | Texas | 75069 | — |
| University Of Utah Hosp & Clin; Investigational Pharmacy | Salt Lake City | Utah | 84132 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22031 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23219-1901 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 208 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04594707, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 16, 2024 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04594707 live on ClinicalTrials.gov.