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Completed Phase 3 Interventional Results available

A Study to Assess the Efficacy and Safety of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)

ClinicalTrials.gov ID: NCT04598451

Public ClinicalTrials.gov record NCT04598451. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blinded, Placebo-Controlled Trial to Investigate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult Patients With Pemphigus (Vulgaris or Foliaceus)

Study identification

NCT ID
NCT04598451
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
argenx
Industry
Enrollment
222 participants

Conditions and interventions

Interventions

  • efgartigimod PH20 SC Biological
  • Placebo Other
  • prednisone Drug

Biological · Other · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2020
Primary completion
Aug 21, 2023
Completion
Aug 21, 2023
Last update posted
Sep 30, 2024

2020 – 2023

United States locations

U.S. sites
21
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
Investigator site 77 - US0010086 Birmingham Alabama 35233
Investigator site 97 - US0010091 Scottsdale Arizona 85259
Investigator site 121 - US0010092 Redwood City California 94063
Investigator site 125 - US0010153 Castle Rock Colorado 80109
Investigator site 2 - US0010087 Boca Raton Florida 33428
Investigator site 99 - US0010117 Miami Florida 33173
Investigator site 78 - US0010109 Orlando Florida 32827
Investigator site 127 - US0010155 West Lafayette Indiana 47906
Investigator site 61 - US0010090 Minneapolis Minnesota 55455
Investigator site 102 - US0010098 St Louis Missouri 63110
Investigator site 19 - US0010088 Buffalo New York 14203-1070
Investigator site 136 - US0010196 New York New York 10128
Investigator site 60 - US0010096 Durham North Carolina 27710
Investigator site 20 - US0010094 Cleveland Ohio 44106-1716
Investigator site 73 - US00100 Philadelphia Pennsylvania 19104
Investigator site 101 - US0010097 Philadelphia Pennsylvania 19140
Investigator site 98 - US0010107 Dallas Texas 75246
Investigator site 1 - US0010084 Dripping Springs Texas 78620
Investigator site 126 - US0010182 Houston Texas 77004
Investigator site 88 - US0010114 Houston Texas 77008
Investigator site 59 - US0010106 Norfolk Virginia 23502

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 113 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04598451, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 30, 2024 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04598451 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →