Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD

ClinicalTrials.gov ID: NCT04600323

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Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a pilot, randomized, double-blinded, placebo-controlled, 12-month trial of 50 patients with CKD stage 3b-4 with metabolic acidosis to examine the effect of sodium bicarbonate therapy on cognitive and cerebrovascular function.

Study identification

NCT ID: NCT04600323
Recruitment status: Completed
Study type: Interventional
Phase: Early Phase 1
Lead sponsor: University of Colorado, Denver; Other
Enrollment: 34 participants

Conditions and interventions

Conditions

Interventions

Sodium Bicarbonate Tablets Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 50 Years to 70 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Feb 1, 2021 (Actual)
Primary completion: Aug 30, 2023 (Actual)
Completion: Aug 30, 2023 (Actual)
Last update posted: Dec 20, 2024

2021 – 2023

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Colorado Anschutz Medical Campus	Aurora	Colorado	80045	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04600323, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Dec 20, 2024 · Synced Nov 15, 2026