Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia
Public ClinicalTrials.gov record NCT04605484. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2 Multicenter, Randomized, Double-blind, Placebo-controlled, Multiple Dosing Interval, 2-period Study of the Safety, Tolerability and Effectiveness of Adoptively Transferred Posoleuccel (ALVR105) Multivirus-specific T Cells in Kidney Transplant Recipients With Either High or Low Levels of BK Viremia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare Posoleucel (formerly known as ALVR105; Viralym-M) to placebo in kidney transplant recipients who have high or low levels of BK virus in their blood.
Study identification
- NCT ID
- NCT04605484
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 61 participants
Conditions and interventions
Conditions
Interventions
- Posoleucel (formerly known as ALVR105) cells Biological
- Placebo (visually identical to Posoleucel) Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 22, 2021 (Actual)
- Primary completion
- Oct 20, 2022 (Actual)
- Completion
- Oct 20, 2022 (Actual)
- Last update posted
- May 16, 2024
2021 – 2022
United States locations
- U.S. sites
- 33
- U.S. states
- 20
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Keck Medical Center of USC | Los Angeles | California | 90033 | — |
| Stanford University | Palo Alto | California | 94306 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| University of California, San Francisco Medical Center | San Francisco | California | 94143 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Northwestern University Transplant Center | Chicago | Illinois | 60611 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Indiana University Hospital | Indianapolis | Indiana | 46202 | — |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| John Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Harvard Medical School - Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48109 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Erie County Medical Center | Buffalo | New York | 14215 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Weil Medical College - NY Presbyterian Hospital | New York | New York | 10021 | — |
| Duke University | Durham | North Carolina | 27708 | — |
| University of Cincinnati Hospital | Cincinnati | Ohio | 45229 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| UPMC Pinnacle-Harrisburg Hospital | Harrisburg | Pennsylvania | 17101 | — |
| UPMC Montefiore Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02905 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Baylor University Medical Center | Dallas | Texas | 75204 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Medical Center | Falls Church | Virginia | 22042 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04605484, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 16, 2024 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04605484 live on ClinicalTrials.gov.