A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults
Public ClinicalTrials.gov record NCT04614948. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Phase 3 Study to Assess the Efficacy and Safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study will evaluate the efficacy of Ad26.COV2.S in the prevention of molecularly confirmed moderate to severe/critical coronavirus disease-2019 (COVID-19), as compared to placebo, in SARS-CoV-2 seronegative adults in the double-blind phase and to describe COVID-19 outcomes, safety, and immunogenicity in the different study cohorts in open-label phase.
Study identification
- NCT ID
- NCT04614948
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 31,835 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 12, 2020 (Actual)
- Primary completion
- Jun 18, 2023 (Actual)
- Completion
- Jun 18, 2023 (Actual)
- Last update posted
- Feb 4, 2025
2020 – 2023
United States locations
- U.S. sites
- 63
- U.S. states
- 26
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Achieve Clinical Research, LLC | Vestavia Hills | Alabama | 35216 | — |
| Hope Research Institute | Phoenix | Arizona | 85018 | — |
| Central Phoenix Medical Clinic | Phoenix | Arizona | 85020 | — |
| Quality of Life Medical & Research Center, LLC | Tucson | Arizona | 85712 | — |
| Synexus Clinical Research US Inc | Tucson | Arizona | 85712 | — |
| Woodland International Research Group | Little Rock | Arkansas | 72211 | — |
| Synexus Clinical Research US Inc | Cerritos | California | 90703 | — |
| eStudySite | Chula Vista | California | 91911 | — |
| Ark Clinical Research | Long Beach | California | 90806 | — |
| Anthony Mills Medical, Inc | Los Angeles | California | 90069 | — |
| Benchmark Research | Sacramento | California | 95684 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Paradigm Clinical Research Centers, Inc. | Wheat Ridge | Colorado | 80033 | — |
| JEM Research LLC | Atlantis | Florida | 33462 | — |
| Prestige Clinical Research Center, Inc. | Coral Gables | Florida | 33134 | — |
| Avail Clinical Research, LLC | DeLand | Florida | 32720 | — |
| Velocity Clinical Research, Hallandale Beach | Hallandale | Florida | 33009 | — |
| Health Awareness inc. | Jupiter | Florida | 33458 | — |
| Altus Research, Inc | Lake Worth | Florida | 33461 | — |
| Compass Research, Melbourne | Melbourne | Florida | 32940 | — |
| Suncoast Research Group | Miami | Florida | 33135 | — |
| Behavioral Clinical Research , Inc | North Miami | Florida | 33161 | — |
| Clinical NeuroScience Solutions Inc | Orlando | Florida | 32806 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Meridien Research | St. Petersburg | Florida | 33709 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Accel Research Sites | Eatonton | Georgia | 31204 | — |
| The University Of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| The South Bend Clinic Center for Research | South Bend | Indiana | 46617-2808 | — |
| Heartland Research Associates, LLC | Newton | Kansas | 67114 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Centex Studies, Inc. | Lake Charles | Louisiana | 70601 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Centennial Medical Group | Elkridge | Maryland | 21075 | — |
| Optimal Research | Rockville | Maryland | 20850 | — |
| Meridian Clinical Research, LLC | Rockville | Maryland | 20854 | — |
| Henry Ford Health Systems | Detroit | Michigan | 48202 | — |
| Cherry Street Services, Inc. | Grand Rapids | Michigan | 49503 | — |
| Washington University School Of Medicine | St Louis | Missouri | 63110-1035 | — |
| Hassman Research Institute, LLC. | Berlin | New Jersey | 08009 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Medpharmics, LLC | Albuquerque | New Mexico | 87102 | — |
| Meridian Clinical Research, LLC | Endwell | New York | 13760 | — |
| Regional Clinical Research, Inc. | Endwell | New York | 13760 | — |
| Allergy Asthma Immunology of Rochester, PC (AAIR) - Research Center | Rochester | New York | 14618 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| American Health Network, LLC | Charlotte | North Carolina | 28207 | — |
| Wilmington Health Associates | Wilmington | North Carolina | 28401 | — |
| CTI Clinical Trial and Consulting Services | Cincinnati | Ohio | 45212 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Centex Studies, Inc. | Houston | Texas | 77058 | — |
| Centex Studies, Inc. | Houston | Texas | 77073 | — |
| Texas Center for Drug Development Inc | Houston | Texas | 77081 | — |
| Centex Studies, Inc. | McAllen | Texas | 78504 | — |
| Endeavor Clinical Trials, LLC | San Antonio | Texas | 78229 | — |
| Tranquility Clinical Research | Webster | Texas | 77598 | — |
| JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
| Alliance for Multispeciality Research | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04614948, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 4, 2025 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04614948 live on ClinicalTrials.gov.