Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis
Public ClinicalTrials.gov record NCT04620213. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Parallel Arm, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Healthy Subjects
Study identification
- NCT ID
- NCT04620213
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Enrollment
- 185 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 17, 2020
- Primary completion
- Dec 22, 2020
- Completion
- Mar 14, 2021
- Last update posted
- Sep 10, 2023
2020 – 2021
United States locations
- U.S. sites
- 12
- U.S. states
- 7
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Site 11 | Newport Beach | California | 92663 | — |
| Clinical Site 10 | San Diego | California | 92123 | — |
| Clinical Site 9 | Longwood | Florida | 32779 | — |
| Clinical Site 6 | Orlando | Florida | 32751 | — |
| Clinical Site 2 | Roswell | Georgia | 30075 | — |
| Clinical Site 7 | Pittsburg | Kansas | 66762 | — |
| Clinical Site 3 | Shawnee Mission | Kansas | 66203 | — |
| Clinical Site 5 | Athens | Ohio | 45701 | — |
| Clinical Site 12 | Cincinnati | Ohio | 45242 | — |
| Clinical Site 1 | Cleveland | Ohio | 44195 | — |
| Clinical Site 8 | Warwick | Rhode Island | 02888 | — |
| Clinical Site 4 | Memphis | Tennessee | 38119 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04620213, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 10, 2023 · Synced Jun 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04620213 live on ClinicalTrials.gov.