Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.
Public ClinicalTrials.gov record NCT04625725. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Double-blind, Placebo-controlled, Multi-center Study in Adults to Determine the Safety and Efficacy of AZD7442, a Combination Product of Two Monoclonal Antibodies (AZD8895 and AZD1061), for Pre-exposure Prophylaxis of COVID-19.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will assess the safety and efficacy of a single dose of AZD7442(× 2 IM injections) compared to placebo for the prevention of COVID-19.
Study identification
- NCT ID
- NCT04625725
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 5,197 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 21, 2020 (Actual)
- Primary completion
- Aug 16, 2022 (Actual)
- Completion
- Dec 8, 2023 (Actual)
- Last update posted
- Dec 31, 2024
2020 – 2023
United States locations
- U.S. sites
- 60
- U.S. states
- 26
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35215 | — |
| Research Site | Tempe | Arizona | 85284 | — |
| Research Site | Little Rock | Arkansas | 72205 | — |
| Research Site | Cerritos | California | 90703 | — |
| Research Site | Fresno | California | 93720 | — |
| Research Site | Garden Grove | California | 92844 | — |
| Research Site | Huntington Beach | California | 92647 | — |
| Research Site | Lancaster | California | 93534 | — |
| Research Site | Modesto | California | 95350 | — |
| Research Site | Victorville | California | 92394 | — |
| Research Site | Westminster | California | 92683 | — |
| Research Site | Hartford | Connecticut | 06112 | — |
| Research Site | Middlebury | Connecticut | 06762 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Coral Springs | Florida | 33071 | — |
| Research Site | Hollywood | Florida | 33024 | — |
| Research Site | Lauderdale Lakes | Florida | 33313 | — |
| Research Site | Miami | Florida | 33125 | — |
| Research Site | Ormond Beach | Florida | 32174 | — |
| Research Site | Pompano Beach | Florida | 33064 | — |
| Research Site | Wesley Chapel | Florida | 33545 | — |
| Research Site | West Palm Beach | Florida | 33409 | — |
| Research Site | Atlanta | Georgia | 30328 | — |
| Research Site | Columbus | Georgia | 31904 | — |
| Research Site | Conyers | Georgia | 30094 | — |
| Research Site | Marietta | Georgia | 30060 | — |
| Research Site | Honolulu | Hawaii | 96859 | — |
| Research Site | Chicago | Illinois | 60607 | — |
| Research Site | Hazel Crest | Illinois | 60429 | — |
| Research Site | Quincy | Illinois | 62301 | — |
| Research Site | Evansville | Indiana | 47714 | — |
| Research Site | Noblesville | Indiana | 46060 | — |
| Research Site | Wichita | Kansas | 67205 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Minneapolis | Minnesota | 55404 | — |
| Research Site | Minneapolis | Minnesota | 55435 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | Omaha | Nebraska | 68134 | — |
| Research Site | Las Vegas | Nevada | 89128 | — |
| Research Site | Albuquerque | New Mexico | 87109 | — |
| Research Site | Jamaica | New York | 11432 | — |
| Research Site | Ridgewood | New York | 11385 | — |
| Research Site | The Bronx | New York | 10461 | — |
| Research Site | Greensboro | North Carolina | 27410 | — |
| Research Site | Columbus | Ohio | 43213 | — |
| Research Site | Oklahoma City | Oklahoma | 73104 | — |
| Research Site | Summerville | South Carolina | 29485 | — |
| Research Site | Rapid City | South Dakota | 57701 | — |
| Research Site | Austin | Texas | 78751 | — |
| Research Site | El Paso | Texas | 79925 | — |
| Research Site | El Paso | Texas | 79935 | — |
| Research Site | Houston | Texas | 77054 | — |
| Research Site | San Antonio | Texas | 78215 | — |
| Research Site | San Antonio | Texas | 78251 | — |
| Research Site | Shenandoah | Texas | 77384 | — |
| Research Site | Sugar Land | Texas | 77479 | — |
| Research Site | Layton | Utah | 84041 | — |
| Research Site | Alexandria | Virginia | 22304 | — |
| Research Site | Chesapeake | Virginia | 23320 | — |
| Research Site | Tacoma | Washington | 98402 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04625725, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 31, 2024 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04625725 live on ClinicalTrials.gov.