Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD
Public ClinicalTrials.gov record NCT04626128. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
OASIS: Open-label, Dose-escalation, Phase 1/2a Study of the Safety and Tolerability of Suprachoroidally Administered CLS-AX Following Intravitreal Anti-VEGF Therapy in Subjects With Neovascular Age-related Macular Degeneration
Study identification
- NCT ID
- NCT04626128
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Clearside Biomedical, Inc.
- Industry
- Enrollment
- 27 participants
Conditions and interventions
Conditions
Interventions
- CLS-AX Drug
- Anti-VEGF Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 14, 2020
- Primary completion
- Oct 12, 2022
- Completion
- Oct 12, 2022
- Last update posted
- Sep 17, 2023
2020 – 2022
United States locations
- U.S. sites
- 11
- U.S. states
- 6
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Consultants of Arizona | Phoenix | Arizona | 85014 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Northern California Retina Vitreous Associates Medical Group, LLC | Mountain View | California | 94040 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95825 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | — |
| Retina Consultants of Texas | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04626128, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 17, 2023 · Synced Jul 23, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04626128 live on ClinicalTrials.gov.