A Study to Assess Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060)
Public ClinicalTrials.gov record NCT04626596. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-label, Multi-center, Single Arm Study to Assess Contraceptive Efficacy and Safety of the Etonogestrel (MK-8415) Implant During Extended Use From 3 Years After Insertion in Females 35 Years of Age or Younger
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to assess the efficacy and safety of the etonogestrel (ENG) contraceptive implant during participants' fourth and fifth years of use when used as the only method of contraception. The ENG implant is currently approved for a 3-year duration, and this study aims to confirm available evidence suggesting that the ENG implant remains highly effective when used up to 5 years.
Study identification
- NCT ID
- NCT04626596
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 498 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Up to 35 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 19, 2020 (Actual)
- Primary completion
- Dec 30, 2024 (Actual)
- Completion
- Dec 30, 2024 (Actual)
- Last update posted
- Feb 18, 2026
2020 – 2024
United States locations
- U.S. sites
- 64
- U.S. states
- 32
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Clinical Therapeutics (Site 0222) | Birmingham | Alabama | 35205 | — |
| Desert Star Family Planning (Site 0193) | Phoenix | Arizona | 85015 | — |
| Precision Trials (Site 0187) | Phoenix | Arizona | 85032 | — |
| Visions Clinical Research Tucson (Site 0134) | Tucson | Arizona | 85712 | — |
| Essential Access Health (Site 0163) | Los Angeles | California | 90010 | — |
| Matrix Clinical Research Inc (Site 0105) | Los Angeles | California | 90057 | — |
| University of California Los Angeles (Site 0119) | Los Angeles | California | 90095 | — |
| University of California, Davis (Site 0124) | Sacramento | California | 95817 | — |
| Stanford University (Site 0112) | Stanford | California | 94305 | — |
| Planned Parenthood of the Rocky Mountains (Site 0196) | Denver | Colorado | 80207 | — |
| Comprehensive Womens Health Center (Site 0194) | Denver | Colorado | 80230 | — |
| Physicians' Research Options, LLC (Site 0166) | Lakewood | Colorado | 80228 | — |
| University Of Florida (Site 0144) | Jacksonville | Florida | 32207 | — |
| Emerald Coast Obstetrics and Gynecology (Site 0203) | Panama City | Florida | 32405 | — |
| Lenus Research & Medical Group Llc (Site 0102) | Sweetwater | Florida | 33172 | — |
| Comprehensive Clinical Trials LLC (Site 0101) | West Palm Beach | Florida | 33409 | — |
| Mount Vernon Clinical Research (Site 0111) | Sandy Springs | Georgia | 30328 | — |
| Rosemark (Site 0177) | Idaho Falls | Idaho | 83404 | — |
| Planned Parenthood of Illinois (PPIL) (Site 0200) | Chicago | Illinois | 60610 | — |
| Indiana University (Site 0220) | Indianapolis | Indiana | 46202 | — |
| McFarland Clinic, PC (Site 0217) | Ames | Iowa | 50010-3014 | — |
| Cypress Medical Research Center (Site 0226) | Wichita | Kansas | 67226 | — |
| Southern Clinical Research Associates (Site 0219) | Metairie | Louisiana | 70001 | — |
| Johns Hopkins Bayview Medical Center (Site 0225) | Baltimore | Maryland | 21224 | — |
| Boston University Medical Center (Site 0167) | Boston | Massachusetts | 02118 | — |
| Planned Parenthood League of Massachusetts (Site 0135) | Boston | Massachusetts | 02215 | — |
| Michigan Medicine (Site 0108) | Ann Arbor | Michigan | 48109 | — |
| Saginaw Valley Medical Research Group, LLC (Site 0198) | Saginaw | Michigan | 48604 | — |
| Planned Parenthood of North Central States (PPNCS) (Site 0113) | Minneapolis | Minnesota | 55408 | — |
| Metro Jackson OBGYN/SKYCRNG (Site 0233) | Jackson | Mississippi | 39202 | — |
| Planned Parenthood of the Saint Louis Region & Southwest Missouri (Site 0158) | St Louis | Missouri | 63108 | — |
| Washington University (Site 0129) | St Louis | Missouri | 63108 | — |
| Office of Edmond Pack, MD (Site 0168) | Las Vegas | Nevada | 89113 | — |
| Capital Health OB/GYN- Lawrenceville (Site 0190) | Lawrenceville | New Jersey | 08648 | — |
| Albuquerque Clinical Trials (Site 0210) | Albuquerque | New Mexico | 87102 | — |
| Bosque Women's Care (Site 0211) | Albuquerque | New Mexico | 87111 | — |
| Icahn School of Medicine at Mount Sinai (Site 0155) | New York | New York | 10029 | — |
| Columbia Univ. Medical Center (Site 0118) | New York | New York | 10032 | — |
| Montefiore Medical Center (Site 0103) | The Bronx | New York | 10461 | — |
| Carolina Women's Research and Wellness Center (Site 0154) | Durham | North Carolina | 27713 | — |
| Eastern Carolina Women's Center (Site 0159) | New Bern | North Carolina | 28562 | — |
| Velocity Clinical Research, Cincinnati (Site 0230) | Cincinnati | Ohio | 45242 | — |
| The Ohio State University (Site 0176) | Columbus | Ohio | 43210 | — |
| HWC Women's Research Center (Site 0199) | Englewood | Ohio | 45322 | — |
| Oregon Health Sciences University Hospital (Site 0128) | Portland | Oregon | 97239 | — |
| OB/GYN Associates of Erie (Site 0183) | Erie | Pennsylvania | 16507 | — |
| University of Pittsburgh - Magee Womens Hospital (Site 0100) | Pittsburgh | Pennsylvania | 15213 | — |
| Palmetto Clinical Research (Site 0133) | Summerville | South Carolina | 29485 | — |
| University of Tennessee Medical Center Knoxville (Site 0218) | Knoxville | Tennessee | 37920 | — |
| Gadolin Research (Site 0232) | Beaumont | Texas | 77702 | — |
| Signature Gyn Services (Site 0201) | Fort Worth | Texas | 76104 | — |
| Planned Parenthood of the Gulf Coast (Site 0106) | Houston | Texas | 77023 | — |
| University of Texas Health Science Center (Site 0178) | Houston | Texas | 77030 | — |
| Centex Studies, Inc. (Site 0171) | Houston | Texas | 77058 | — |
| Advances in Health, Inc. (Site 0209) | Pearland | Texas | 77030 | — |
| Tekton Research - Floyd Curl Drive (Site 0228) | San Antonio | Texas | 78229 | — |
| Physicians' Research Options, LLC (Site 0204) | Pleasant Grove | Utah | 84062 | — |
| JBR Clinical Research (Site 0174) | Salt Lake City | Utah | 84107 | — |
| Tidewater Clinical Research Inc (Site 0162) | Norfolk | Virginia | 23502 | — |
| Eastern Virginia Medical School (Site 0146) | Norfolk | Virginia | 23507 | — |
| Multicare Health System Institute for Research and Innovation (Site 0188) | Cheney | Washington | 99004 | — |
| Seattle Women's: Health, Research, Gynecology (Site 0149) | Seattle | Washington | 98105 | — |
| Planned Parenthood Great Northwest, Hawai'i, Alaska, Indiana, Kentucky (Site 0110) | Seattle | Washington | 98122 | — |
| North Spokane Women's Clinic (Site 0137) | Spokane | Washington | 99207 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04626596, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 18, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04626596 live on ClinicalTrials.gov.