A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers
Public ClinicalTrials.gov record NCT04626635. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Study of REGN7075 (EGFRxCD28 Costimulatory Bispecific Antibody) in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Study identification
- NCT ID
- NCT04626635
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Regeneron Pharmaceuticals
- Industry
- Enrollment
- 933 participants
Conditions and interventions
Conditions
Interventions
- Bevacizumab Drug
- Cemiplimab Drug
- Platinum-based doublet chemotherapy Drug
- REGN7075 Drug
- Trifluridine-tipiracil Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 20, 2020
- Primary completion
- Aug 18, 2026
- Completion
- Apr 6, 2027
- Last update posted
- Apr 8, 2026
2020 – 2027
United States locations
- U.S. sites
- 21
- U.S. states
- 15
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Valkyrie Clinical Trials | Los Angeles | California | 90067 | Recruiting |
| University of California Los Angeles (UCLA) Medical Center | Los Angeles | California | 90095 | Recruiting |
| The Regents of the University of California, San Francisco | San Francisco | California | 94118 | Recruiting |
| University of Colorado Hospital - Anschutz Cancer Pavilion - Lung Cancer Clinic | Aurora | Colorado | 80045 | Recruiting |
| University of Florida Health | Gainesville | Florida | 32608 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Completed |
| University of Illinois Cancer Center | Chicago | Illinois | 60612 | Recruiting |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | Recruiting |
| Dana Farber Cancer Institute Brookline Avenue | Boston | Massachusetts | 02215 | Withdrawn |
| START Midwest - Cancer & Hematology Centers of Western Michigan, PC | Grand Rapids | Michigan | 49546 | Recruiting |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | Recruiting |
| The Stefanie Spielman Comprehensive Breast Center | Columbus | Ohio | 43212 | Completed |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | Recruiting |
| Sarah Cannon Research Institute - 25th Ave | Nashville | Tennessee | 37203 | Recruiting |
| Vanderbilt Ingram Cancer Center | Nashville | Tennessee | 37232 | Recruiting |
| MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| South Texas Oncology And Hematology | San Antonio | Texas | 78229 | Completed |
| University of Washington/Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04626635, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 8, 2026 · Synced May 12, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04626635 live on ClinicalTrials.gov.