A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis
Public ClinicalTrials.gov record NCT04631016. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety and Tolerability of MEDI3506 in Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease and Chronic Bronchitis (FRONTIER 4)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a research study to determine the efficacy and safety of investigational drug MEDI3506 for the treatment of adult participants with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis.
Study identification
- NCT ID
- NCT04631016
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 137 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 14, 2020 (Actual)
- Primary completion
- May 30, 2023 (Actual)
- Completion
- Nov 13, 2023 (Actual)
- Last update posted
- Feb 27, 2025
2020 – 2023
United States locations
- U.S. sites
- 16
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Sheffield | Alabama | 35660 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Newark | Delaware | 19713 | — |
| Research Site | Kissimmee | Florida | 34746 | — |
| Research Site | Ormond Beach | Florida | 32174 | — |
| Research Site | Winter Park | Florida | 32789 | — |
| Research Site | Lakeside Park | Kentucky | 41017 | — |
| Research Site | White Marsh | Maryland | 21162 | — |
| Research Site | Ann Arbor | Michigan | 48197 | — |
| Research Site | New Bern | North Carolina | 28562 | — |
| Research Site | Columbus | Ohio | 43215 | — |
| Research Site | Oklahoma City | Oklahoma | 73120 | — |
| Research Site | Pittsburgh | Pennsylvania | 15213 | — |
| Research Site | North Charleston | South Carolina | 29406 | — |
| Research Site | Spartanburg | South Carolina | 29303 | — |
| Research Site | Boerne | Texas | 78006 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 74 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04631016, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2025 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04631016 live on ClinicalTrials.gov.