Bevacizumab Treatment For Type 1 ROP
Public ClinicalTrials.gov record NCT04634578. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Bevacizumab Treatment For Type 1 Retinopathy of Prematurity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Type 1 retinopathy of prematurity in zone I represents the most severe type of ROP and has the worst prognosis. It is unknown whether low-dose bevacizumab will be successful in these severe cases. Also unknown is the timing and extent of peripheral retinal vascularization after low-dose bevacizumab compared with the standard dose. The current study will evaluate whether doses of 0.063 mg and 0.25mg are effective as treatment for type 1 ROP, with ROP and retinal vessels all in zone I.
Study identification
- NCT ID
- NCT04634578
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 77 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Up to 6 Months
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2022 (Actual)
- Primary completion
- Jul 1, 2025 (Actual)
- Completion
- Jul 1, 2027 (Estimated)
- Last update posted
- Feb 11, 2026
2022 – 2027
United States locations
- U.S. sites
- 25
- U.S. states
- 17
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Childrens Hospital/ University of Arkansas Medical Sciences | Little Rock | Arkansas | 72202 | — |
| Univ of California, Irvine- Gavin Herbert Eye Institute | Irvine | California | 92697 | — |
| Jules Stein Eye Institute at the University of California, Los Angeles | Los Angeles | California | 90095 | — |
| University of California, Davis | Sacramento | California | 95817 | — |
| University of California San Francisco Department of Ophthalmology | San Francisco | California | 94143 | — |
| The Emory Eye Center | Atlanta | Georgia | 30322 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| U of Illinois at Chicago Eye and Ear Infirmary | Chicago | Illinois | 60612 | — |
| University of Chicago | Hyde Park | Illinois | 60637 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| UK Ophthalmology and Visual Sciences, The Eye Clinic | Lexington | Kentucky | 40508 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204-5809 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02215 | — |
| New York Presbyterian David H Koch Center | New York | New York | 10065 | — |
| Duke University Eye Center | Durham | North Carolina | 27710 | — |
| Cincinnati Children's Hospital | Cincinnati | Ohio | 45229 | — |
| Pediatric Ophthalmology Associates, Inc. | Columbus | Ohio | 43205 | — |
| Casey Eye Institute | Portland | Oregon | 97239 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Children's Eye Center of Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Storm Eye Institute | Mt. Pleasant | South Carolina | 29464 | — |
| Texas Children's Hospital - Dept. Of Ophthalmology | Houston | Texas | 77030 | — |
| University of Utah Moran Eye Center | Salt Lake City | Utah | 84132 | — |
| Virginia Pediatric Eye Center | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04634578, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 11, 2026 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04634578 live on ClinicalTrials.gov.