A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP
Public ClinicalTrials.gov record NCT04634604. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Trial of Low-Dose Bevacizumab Versus Laser for Type 1 Retinopathy of Prematurity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized clinical trial will compare retinal outcomes with low-dose intravitreous bevacizumab (0.063 mg) versus laser photocoagulation as treatment for infants with type 1 retinopathy of prematurity (ROP). The study also will assess neurodevelopment, refractive error, visual acuity, and peripheral visual fields.
Study identification
- NCT ID
- NCT04634604
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 16 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Up to 6 Months
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 27, 2022 (Actual)
- Primary completion
- Aug 14, 2023 (Actual)
- Completion
- Aug 14, 2023 (Actual)
- Last update posted
- Sep 14, 2026
2022 – 2023
United States locations
- U.S. sites
- 32
- U.S. states
- 22
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizonia Pediatric Eye Specialists | Phoenix | Arizona | 85006 | — |
| Arkansas Childrens Hospital/ University of Arkansas Medical Sciences | Little Rock | Arkansas | 72202 | — |
| Univ of California, Irvine- Gavin Herbert Eye Institute | Irvine | California | 92697 | — |
| University of California, Davis | Sacramento | California | 95817 | — |
| University of California San Francisco Department of Ophthalmology | San Francisco | California | 94143 | — |
| University of Colorado Health Sciences Center | Aurora | Colorado | 80045 | — |
| Denver Health and Hospital Authority | Denver | Colorado | 80204 | — |
| Connecticut Childrens Medical Center | Farmington | Connecticut | 06032 | — |
| The Emory Eye Center | Atlanta | Georgia | 30322 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| U of Illinois at Chicago Eye and Ear Infirmary | Chicago | Illinois | 60612 | — |
| University of Chicago | Hyde Park | Illinois | 60637 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| UK Ophthalmology and Visual Sciences, The Eye Clinic | Lexington | Kentucky | 40508 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204-5809 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02215 | — |
| University of Missouri- Columbia Mason Eye Institute | Columbia | Missouri | 65201 | — |
| St. Louis University Ophthalmology | St Louis | Missouri | 63104 | — |
| Children's Hospital & Medical Center | Omaha | Nebraska | 68114 | — |
| New York Presbyterian David H Koch Center | New York | New York | 10065 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | — |
| Duke University Eye Center | Durham | North Carolina | 27710 | — |
| Cincinnati Children's Hospital | Cincinnati | Ohio | 45229 | — |
| Pediatric Ophthalmology Associates, Inc. | Columbus | Ohio | 43205 | — |
| Casey Eye Institute | Portland | Oregon | 97239 | — |
| UPMC Children's Eye Center of Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Storm Eye Institute | Mt. Pleasant | South Carolina | 29464 | — |
| Texas Children's Hospital - Dept. Of Ophthalmology | Houston | Texas | 77030 | — |
| The Woman's Hospital of Texas | Houston | Texas | 77054 | — |
| University of Utah Moran Eye Center | Salt Lake City | Utah | 84132 | — |
| Virginia Pediatric Eye Center | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04634604, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 14, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04634604 live on ClinicalTrials.gov.