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Completed Phase 2 Interventional Results available

A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)

ClinicalTrials.gov ID: NCT04640077

Public ClinicalTrials.gov record NCT04640077. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 12:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Donanemab Follow-On Study: Safety, Tolerability, And Efficacy in Symptomatic Alzheimer's Disease With Validation of Remote Neuropsychological Assessments

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main goals of this study are to further determine whether the study drug donanemab is safe and effective in participants with Alzheimer's disease and to validate neuropsychological assessments administered over videoconferencing

Study identification

NCT ID
NCT04640077
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
95 participants

Conditions and interventions

Eligibility (public fields only)

Age range
60 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 22, 2020
Primary completion
Feb 26, 2024
Completion
Feb 26, 2024
Last update posted
Jun 12, 2025

2020 – 2024

United States locations

U.S. sites
23
U.S. states
14
U.S. cities
22
Facility City State ZIP Site status
Banner Alzheimer's Institute Phoenix Arizona 85006
UC Irvine-Institute for Memory Impairments and Neurological Disorders (UCI MIND) Irvine California 92697
Bradenton Research Center, Inc. Bradenton Florida 34205
Merritt Island Medical Research, LLC Merritt Island Florida 32952
Synexus Clinical Research US, Inc. Orlando Florida 32806
Advanced Research Consultants Palm Beach Gardens Florida 33410
Progressive Medical Research Port Orange Florida 32127
Intercoastal Medical Group - Hyde Park Sarasota Florida 34239
Stedman Clinical Trials Tampa Florida 33613
Indiana University Indianapolis Indiana 46202
Josephson Wallack Munshower Neurology, PC Indianapolis Indiana 46256
The University of Kansas - Clinical Research Center Fairway Kansas 66205
Cotton O'Neil Clinical Research Center - Central Office Topeka Kansas 66606
Boston Center for Memory Newton Massachusetts 02459
Washington University St Louis Missouri 63110
Las Vegas Medical Research Las Vegas Nevada 89113
Advanced Memory Research Institute of New Jersey Toms River New Jersey 08755
Guilford Neurologic Research, PA Greensboro North Carolina 27405
Ohio State University Columbus Ohio 43210
Neurology Diagnostics, Inc. Dayton Ohio 45459
Abington Neurological Associates, Ltd. Abington Pennsylvania 19001
Rhode Island Hospital Providence Rhode Island 02903
National Clinical Research, Inc Richmond Virginia 23294

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04640077, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 12, 2025 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04640077 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →