LYT-100 in Post-acute COVID-19 Respiratory Disease
Public ClinicalTrials.gov record NCT04652518. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Double-blind, Placebo-controlled Trial and Open Label Extension to Evaluate the Safety and Efficacy of Deupirfenidone (LYT-100) in Post-acute COVID-19 Respiratory Disease
Study identification
- NCT ID
- NCT04652518
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- PureTech
- Industry
- Enrollment
- 185 participants
Conditions and interventions
Conditions
Interventions
- LYT-100 Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 10, 2020
- Primary completion
- Jun 27, 2022
- Completion
- Jul 17, 2022
- Last update posted
- Jun 22, 2026
2020 – 2022
United States locations
- U.S. sites
- 15
- U.S. states
- 10
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| North Alabama Medical Center | Florence | Alabama | 35630 | — |
| University of Southern California - Keck School of Medicine | Los Angeles | California | 90033 | — |
| Vista Health Research | Miami | Florida | 33176 | — |
| Central Florida Pulmonary Group | Orlando | Florida | 32803 | — |
| Coastal Pulmonary and Critical Care | St. Petersburg | Florida | 33704 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Center for Advanced Research and Education | Gainesville | Georgia | 30501 | — |
| GenHarp Clinical Solutions | Evergreen Park | Illinois | 60805 | — |
| Circuit Clinical/Crystal Run Healthcare LLP | Middletown | New York | 10941 | — |
| Southeastern Research Center | Winston-Salem | North Carolina | 27103 | — |
| University of Pittsburg Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Affinity Health Corp | Nashville | Tennessee | 37203 | — |
| Frostwood Family Medicine | Houston | Texas | 77024 | — |
| The University of Texas Health Sciences Center at San Antonio | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04652518, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2026 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04652518 live on ClinicalTrials.gov.