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Completed Phase 3 Interventional Results available

CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks

ClinicalTrials.gov ID: NCT04656418

Public ClinicalTrials.gov record NCT04656418. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 8:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-arm Study to Investigate the Efficacy and Safety of Subcutaneous Administration of CSL312 (Garadacimab) in the Prophylactic Treatment of Hereditary Angioedema

Study identification

NCT ID
NCT04656418
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
CSL Behring
Industry
Enrollment
64 participants

Conditions and interventions

Interventions

  • CSL312 Biological
  • Placebo Drug

Biological · Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 26, 2021
Primary completion
Jun 6, 2022
Completion
Jun 6, 2022
Last update posted
Jun 28, 2023

2021 – 2022

United States locations

U.S. sites
8
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
Clinical Research Center of Alabama Birmingham Alabama 35209
Medical Research of Arizona Scottsdale Arizona 85251
Raffi Tachdjian MD, Inc. Santa Monica California 90404
Allergy and Asthma Clinical Research Walnut Creek California 94598
Institute of Asthma and Allergy Chevy Chase Maryland 20815
Bernstein Clinical Research Center LLC Cincinnati Ohio 45231
Pennsylvania State University Hershey Pennsylvania 17033
AARA Research Center Dallas Texas 75231

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04656418, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 28, 2023 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04656418 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →