A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
Public ClinicalTrials.gov record NCT04657016. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo After an Intensive Lifestyle Program in Participants Without Type 2 Diabetes Who Have Obesity or Are Overweight With Weight-Related Comorbidities: A Randomized, Double Blind, Placebo-Controlled Trial (SURMOUNT-3)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study of tirzepatide in participants with obesity. The purpose of this study is to learn more about how tirzepatide maintains body weight or adds to weight loss after an intensive lifestyle modification program. The study will last about 2 years (29 visits).
Study identification
- NCT ID
- NCT04657016
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 579 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 29, 2021 (Actual)
- Primary completion
- Apr 20, 2023 (Actual)
- Completion
- May 12, 2023 (Actual)
- Last update posted
- May 16, 2024
2021 – 2023
United States locations
- U.S. sites
- 45
- U.S. states
- 23
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| National Research Institute - Huntington Park | Huntington Park | California | 90255 | — |
| National Research Institute - Wilshire | Los Angeles | California | 90057 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| National Research Institute (NRI) - Santa Ana | Santa Ana | California | 92704 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Clinical Research of South Florida | Coral Gables | Florida | 33134 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| Clinical Research of West Florida | Tampa | Florida | 33606 | — |
| Metabolic Research Institute, Inc. | West Palm Beach | Florida | 33401 | — |
| Elite Clinical Trials | Blackfoot | Idaho | 83221 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Elite Clinical Trials | Rexburg | Idaho | 83440 | — |
| Evanston Premier Healthcare Research LLC | Evanston | Illinois | 60201 | — |
| American Health Network of IN, LLC | Avon | Indiana | 46123 | — |
| American Health Network of IN, LLC | Franklin | Indiana | 46131 | — |
| American Health Network of IN, LLC | Muncie | Indiana | 47304 | — |
| Cotton O'Neil Mulvane | Topeka | Kansas | 66606 | — |
| Tandem Clinical Research,LLC | Marrero | Louisiana | 70072 | — |
| The National Diabetes & Obesity Research Institute | Biloxi | Mississippi | 39532 | — |
| Clinvest Research LLC | Springfield | Missouri | 65810 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Palm Research Center Sunset | Las Vegas | Nevada | 89148 | — |
| Rochester Clinical Research, Inc. | Rochester | New York | 14609 | — |
| University of North Carolina Medical Center | Chapel Hill | North Carolina | 27514 | — |
| PharmQuest | Greensboro | North Carolina | 27408 | — |
| Wake Forest University Baptist Medical Center (WFUBMC) | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44122 | — |
| Intend Research, LLC | Norman | Oklahoma | 73069 | — |
| Summit Research Network | Portland | Oregon | 97210 | — |
| Detweiler Family Medicine & Associates | Lansdale | Pennsylvania | 19446 | — |
| Penn Medicine: University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | — |
| Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair | Pittsburgh | Pennsylvania | 15243 | — |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | — |
| Holston Medical Group | Bristol | Tennessee | 37620 | — |
| Vanderbilt Health One Hundred Oaks | Nashville | Tennessee | 37204 | — |
| Dallas Diabetes Research Center | Dallas | Texas | 75230 | — |
| Juno Research | Houston | Texas | 77040 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| Texas Diabetes & Endocrinology, P.A. | Round Rock | Texas | 78681 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Health Research of Hampton Roads, Inc. | Newport News | Virginia | 23606 | — |
| MultiCare Institute for Research & Innovation | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04657016, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 16, 2024 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04657016 live on ClinicalTrials.gov.