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Completed Phase 1 Interventional

Cabozantinib With Topotecan-Cyclophosphamide

ClinicalTrials.gov ID: NCT04661852

Public ClinicalTrials.gov record NCT04661852. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 5:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 1 Study of Cabozantinib in Combination With Topotecan-Cyclophosphamide for Patients With Relapsed Ewing Sarcoma or Osteosarcoma

Study identification

NCT ID
NCT04661852
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Dana-Farber Cancer Institute
Other
Enrollment
12 participants

Conditions and interventions

Interventions

  • Cabozantinib Drug
  • Topotecan Drug
  • Cyclophosphamide Drug
  • Myeloid growth factor Drug

Drug

Eligibility (public fields only)

Age range
6 Years to 30 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 22, 2020
Primary completion
Oct 23, 2022
Completion
Oct 23, 2022
Last update posted
Feb 14, 2023

2020 – 2022

United States locations

U.S. sites
2
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Boston Children's Hospital Boston Massachusetts 02115
Dana-Farber Cancer Institute Boston Massachusetts 02115

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04661852, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 14, 2023 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04661852 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →