Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation
Public ClinicalTrials.gov record NCT04666259. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open Label, Multi-center Phase IIIb Study of Asciminib (ABL001) Monotherapy in Previously Treated Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study was a multicenter Phase IIIb open-label, three-cohort study of asciminib in patients with CML-CP without T315I mutation who have had at least 2 prior TKIs and CML-CP harboring the T315I mutation with at least 1 prior TKI
Study identification
- NCT ID
- NCT04666259
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 56 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 25, 2021 (Actual)
- Primary completion
- Jun 20, 2023 (Actual)
- Completion
- Jun 26, 2024 (Actual)
- Last update posted
- Oct 16, 2025
2021 – 2024
United States locations
- U.S. sites
- 26
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Oncology and Hematology | Anchorage | Alaska | 99508 | — |
| Arizona Oncology Associates | Phoenix | Arizona | 85016 | — |
| Cancer Treatment Centers of America | Phoenix | Arizona | 85027 | — |
| Pacific Shores Medical Group | Long Beach | California | 90813 | — |
| Lundquist Inst BioMed at Harbor | Torrance | California | 90509-2910 | — |
| Rocky Mountain Cancer Centers | Boulder | Colorado | 80304 | — |
| Memorial Cancer Institute | Hollywood | Florida | 33021 | — |
| Florida Cancer Specialists | Sarasota | Florida | 34232 | — |
| Florida Cancer Specialists-North | St. Petersburg | Florida | 33705 | — |
| Florida Cancer Specialists East | Stuart | Florida | 34994 | — |
| Florida Cancer Specialists Pan | Tallahassee | Florida | 32308 | — |
| Indiana Blood and Marrow Institute | Beech Grove | Indiana | 46107 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Uni of Massachusetts Medical Center | Worcester | Massachusetts | 01655 | — |
| Michigan Med University of Michigan | Ann Arbor | Michigan | 48109 5271 | — |
| Siteman Cancer Center | St Louis | Missouri | 63110 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Uni of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45242 | — |
| Northwest Cancer Specialists | Portland | Oregon | 97210 | — |
| Texas Oncology | Dallas | Texas | 75251 | — |
| Texas Oncology P A | Fort Worth | Texas | 76104 | — |
| Univ of TX MD Anderson Cancer Cntr | Houston | Texas | 77030 | — |
| Texas Oncology Northeast Texas | Tyler | Texas | 75702 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04666259, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2025 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04666259 live on ClinicalTrials.gov.