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Terminated Phase 2 Interventional Accepts healthy volunteers Results available

A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults

ClinicalTrials.gov ID: NCT04668339

Public ClinicalTrials.gov record NCT04668339. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 3:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Observer-Blind, Placebo-Controlled Study to Assess the Safety, Reactogenicity, and Immunogenicity of the SARS CoV-2 Vaccine ARCT-021 in Healthy Adult Participants

Study identification

NCT ID
NCT04668339
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Arcturus Therapeutics, Inc.
Industry
Enrollment
581 participants

Conditions and interventions

Interventions

  • ARCT-021 single dose priming Biological
  • ARCT-021 two lower dose priming Biological
  • ARCT-021 two higher dose priming Biological
  • Placebo (two doses), priming Biological
  • Randomized booster Biological
  • Placebo booster Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 6, 2021
Primary completion
Feb 28, 2022
Completion
Feb 28, 2022
Last update posted
May 14, 2025

2021 – 2022

United States locations

U.S. sites
12
U.S. states
7
U.S. cities
12
Facility City State ZIP Site status
Arcturus Investigational Site 103 Chandler Arizona 85224
Arcturus Investigational Site 107 Tucson Arizona 85741
Arcturus Investigational Site 112 San Diego California 92108
Arcturus Investigational Site 104 Melbourne Florida 32934
Arcturus Investigational Site 105 Orlando Florida 32806
Arcturus Investigational Site 106 Pinellas Park Florida 33781
Arcturus Investigational Site 109 The Villages Florida 32162
Arcturus Investigational Site 101 Peoria Illinois 61614
Arcturus Investigational Site 110 Rockville Maryland 20850
Arcturus Investigational Site 102 Anderson South Carolina 29621
Arcturus Investigational Site 111 Austin Texas 78705
Arcturus Investigational Site 108 Dallas Texas 75234

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04668339, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 14, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04668339 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →