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Completed Phase 2 Interventional

TTHX1114(NM141) in Combination With DWEK/DSO

ClinicalTrials.gov ID: NCT04676737

Public ClinicalTrials.gov record NCT04676737. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2 Study To Determine the Safety and Efficacy of TTHX1114(NM141) on the Regeneration and Migration of Corneal Endothelial Cells in Patients Undergoing DWEK/DSO

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Open label, single-treatment, with a concurrent non-treatment control

Study identification

NCT ID
NCT04676737
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Trefoil Therapeutics, Inc.
Industry
Enrollment
49 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 1, 2021 (Actual)
Primary completion
Nov 16, 2022 (Actual)
Completion
Jan 13, 2023 (Actual)
Last update posted
Nov 7, 2023

2021 – 2023

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
Trefoil Investigational Site 124 Long Beach California 90805 —
North Bay Eye Associates Petaluma California 94954 —
Trefoil Investigational Site 123 Deerfield Beach Florida 33064 —
Trefoil Investigational Site 119 Fort Myers Florida 33907 —
Price Vision Group Indianapolis Indiana 46260 —
Tauber Eye Center Kansas City Missouri 64111 —
Vance Thompson Vision - Bozeman Bozeman Montana 59718 —
Vance Thompson Vision - Omaha Omaha Nebraska 68137 —
Vance Thompson Vision - Fargo West Fargo North Dakota 58078 —
Trefoil Investigational Site 120 Cincinnati Ohio 45242 —
Vance Thompson Vision - Sioux Falls Sioux Falls South Dakota 57108 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04676737, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 7, 2023 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04676737 live on ClinicalTrials.gov.

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