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Completed Phase 2 Interventional

TTHX1114(NM141) in Combination With DWEK/DSO

ClinicalTrials.gov ID: NCT04676737

Public ClinicalTrials.gov record NCT04676737. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 3:21 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2 Study To Determine the Safety and Efficacy of TTHX1114(NM141) on the Regeneration and Migration of Corneal Endothelial Cells in Patients Undergoing DWEK/DSO

Study identification

NCT ID
NCT04676737
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Trefoil Therapeutics, Inc.
Industry
Enrollment
49 participants

Conditions and interventions

Interventions

  • TTHX1114(NM141) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2021
Primary completion
Nov 15, 2022
Completion
Jan 12, 2023
Last update posted
Nov 6, 2023

2021 – 2023

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
Trefoil Investigational Site 124 Long Beach California 90805
North Bay Eye Associates Petaluma California 94954
Trefoil Investigational Site 123 Deerfield Beach Florida 33064
Trefoil Investigational Site 119 Fort Myers Florida 33907
Price Vision Group Indianapolis Indiana 46260
Tauber Eye Center Kansas City Missouri 64111
Vance Thompson Vision - Bozeman Bozeman Montana 59718
Vance Thompson Vision - Omaha Omaha Nebraska 68137
Vance Thompson Vision - Fargo West Fargo North Dakota 58078
Trefoil Investigational Site 120 Cincinnati Ohio 45242
Vance Thompson Vision - Sioux Falls Sioux Falls South Dakota 57108

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04676737, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 6, 2023 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04676737 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →