ClinicalTrials.gov record
A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis
ClinicalTrials.gov ID: NCT04682639
Public ClinicalTrials.gov record NCT04682639. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Etrasimod in Adult Subjects With Eosinophilic Esophagitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for active eosinophilic esophagitis (EoE) in adult participants.
Study identification
- NCT ID
- NCT04682639
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 108 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 15, 2020 (Actual)
- Primary completion
- Sep 30, 2022 (Actual)
- Completion
- Jun 30, 2023 (Actual)
- Last update posted
- May 6, 2024
2020 – 2023
United States locations
- U.S. sites
- 221
- U.S. states
- 23
- U.S. cities
- 88
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Center of Alabama, LLC | Birmingham | Alabama | 35209 | — |
| GastroHealth - St. Vincent's East | Birmingham | Alabama | 35235 | — |
| Digestive Health Specialists | Dothan | Alabama | 36301 | — |
| Dothan Eyecare - Dr. Brent McKinley (OCT Procedure Only) | Dothan | Alabama | 36301 | — |
| Dothan Surgery Center (Colonoscopy Location) | Dothan | Alabama | 36301 | — |
| Pulmonary Associates (PFT Procedure Only, Second Location ) | Dothan | Alabama | 36301 | — |
| Flowers Hospital (PFT Procedure Only) | Dothan | Alabama | 36305 | — |
| Avant Research Associates, LLC | Huntsville | Alabama | 35802 | — |
| Crestwood Medical Center | Huntsville | Alabama | 35802 | — |
| Baily Cove Eye Care | Huntsville | Alabama | 35803 | — |
| Madison Surgery Center | Madison | Alabama | 35758 | — |
| Alabama Eye MD | Vestavia Hills | Alabama | 35216 | — |
| Arizona Retina Institute/ Phoenix Retina Associates(OCT) | Peoria | Arizona | 85381 | — |
| SimonMed Imaging (Imaging) | Peoria | Arizona | 85381 | — |
| Arizona Digestive Health - Sun City | Sun City | Arizona | 85351 | — |
| Sun City Endoscopy Center (Endoscopy) | Sun City | Arizona | 85351 | — |
| Little Rock Eye Clinic | Little Rock | Arkansas | 72205 | — |
| Four Seasons Allergy and Asthma | Little Rock | Arkansas | 72211 | — |
| Applied Research Center of Arkansas | Little Rock | Arkansas | 72212 | — |
| Premier Gastroenterology Endoscopy Center | Little Rock | Arkansas | 72212 | — |
| Premier Gastroenterology | Little Rock | Arkansas | 72212 | — |
| Isight Vision Care | Fountain Valley | California | 92708 | — |
| Mile Square Surgery Center | Fountain Valley | California | 92708 | — |
| Pulmonary & Sleep Consultants | Fountain Valley | California | 92708 | — |
| Paragon Rx Clinical, Inc. | Garden Grove | California | 92840 | — |
| Inland Pulmonary Specialists [PFT Only] | Lake Elsinore | California | 92532 | — |
| Advanced Endoscopy and Pain Center - EGD & Biopsy Collection | Lancaster | California | 93534 | — |
| Advanced Endoscopy and Pain Center | Lancaster | California | 93534 | — |
| Antelope Valley Eye Care - OCT | Lancaster | California | 93534 | — |
| Antelope Valley Eye Care | Lancaster | California | 93534 | — |
| Antelope Valley Lung and Sleep Institute | Lancaster | California | 93534 | — |
| Apollo Surgery Center | Lancaster | California | 93534 | — |
| AV Pediatrics, Allergy and Family Medicine - PFT, Physical Exams, Lab Reviews, ECG Reviews | Lancaster | California | 93534 | — |
| Gastro Care Institute | Lancaster | California | 93534 | — |
| Jatinder S. Pruthi, MD FACG CPI - Physical Exams, Lab Reviews, ECG Reviews | Lancaster | California | 93534 | — |
| Om Research LLC | Lancaster | California | 93534 | — |
| Clinical Trials Unit | Los Angeles | California | 90033 | — |
| Keck Hospital of USC | Los Angeles | California | 90033 | — |
| USC IDS Pharmacy | Los Angeles | California | 90033 | — |
| Advanced Vision Care (OCT) | Los Angeles | California | 90067 | — |
| United Surgery Center Murrieta [Endoscopy Only] | Murrieta | California | 92562 | — |
| United Medical Doctors | Murrieta | California | 92563 | — |
| California Eye Professionals [OCT Only] | Temecula | California | 92591 | — |
| United Surgery Center Temecula [Endoscopy Only] | Temecula | California | 92592 | — |
| RecioMed Clinical Research Network, Inc | Boynton Beach | Florida | 33472 | — |
| Steelgate | Bradenton | Florida | 34203 | — |
| Bay Area Chest Physicians, P.A., - Pulmonary Function Test | Clearwater | Florida | 33756 | — |
| West Coast Endoscopy Center | Clearwater | Florida | 33756 | — |
| West Coast Endoscopy | Clearwater | Florida | 33756 | — |
| MACULA CENTER Dana M. Deupree, M.D., F.A.C.S (OCT) | Clearwater | Florida | 33761 | — |
| Northwood Vision Optical Coherence Tomography (OCT) | Clearwater | Florida | 33761 | — |
| Safety Harbor Surgery Center | Clearwater | Florida | 33761 | — |
| Gastro Florida (Regulatory & Administrative Duties) | Clearwater | Florida | 33762 | — |
| Beraja Medical Institute (OCT) | Coral Gables | Florida | 33134 | — |
| Bayfront Health Seven Rivers (Liver Biopsy Location) | Crystal River | Florida | 34428 | — |
| Citrus Surgery and Endoscopy Center (EGD Location) | Crystal River | Florida | 34429 | — |
| Advanced Eye Center | Hialeah | Florida | 33012 | — |
| Nature Coast Clinical Research | Inverness | Florida | 34452 | — |
| West Coast Eye Institute (OCT Procedure Only) | Inverness | Florida | 34452 | — |
| Suncoast Endoscopy Center (EGD Location) | Inverness | Florida | 34453 | — |
| Jupiter Outpatient Surgery Center | Jupiter | Florida | 33458 | — |
| Central Florida Sleep Diagnostic & Treatment Center | Lakeland | Florida | 33812 | — |
| Auzmer Research | Lakeland | Florida | 33813 | — |
| West Coast Eye Institute (OCT Procedure Only) | Lecanto | Florida | 34453 | — |
| The Endoscopy Center (Endoscopy Procedure) | Miami | Florida | 33134 | — |
| Research Associates of South Florida | Miami | Florida | 33137 | — |
| Research Associates of South Florida | Miami | Florida | 33156 | — |
| Juan Barrio, MD (PFT when needed) | Miami | Florida | 33173 | — |
| Florida Eye Specialists and Cataract Institute | Riverview | Florida | 33579 | — |
| Dr. Dennis Bassetti, MD | Sebring | Florida | 33870 | — |
| Highlands Eye Institute, P.A. | Sebring | Florida | 33870 | — |
| The Surgery and Endoscopy Center | Sebring | Florida | 33870 | — |
| Ambulatory Surgery Center | Tampa | Florida | 33613 | — |
| Pulmonology & Sleep Disorders | Tampa | Florida | 33613 | — |
| Day Surgery Center | Winter Haven | Florida | 33884 | — |
| Digestive Healthcare of Georgia | Atlanta | Georgia | 30309 | — |
| Peachtree Allergy and Asthma Clinica - Pulmonary Function Test | Atlanta | Georgia | 30309 | — |
| Piedmont Hospital- DLCO | Atlanta | Georgia | 30309 | — |
| Ross Eyecare - Opthalmoscopy and OCT | Atlanta | Georgia | 30324 | — |
| Georgia Eye Partners | Decatur | Georgia | 30030 | — |
| Atlanta Center for Gastroenterology, P.C. | Decatur | Georgia | 30033 | — |
| Atlanta Endoscopy Center LTD | Decatur | Georgia | 30033 | — |
| Pulmonary & Sleep Specialist | Decatur | Georgia | 30033 | — |
| Grand Teton Research Group, PLLC | Idaho Falls | Idaho | 83404 | — |
| Grand Teton Surgical Center | Idaho Falls | Idaho | 83404 | — |
| Idaho Falls Pulmonary/ Sleep and Critical Care Specialists (PFT procedure only) | Idaho Falls | Idaho | 83404 | — |
| Premier Eye Care of Eastern Idaho (OCT procedure only) | Idaho Falls | Idaho | 83404 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Glen Endoscopy Center (Endoscopy Facility) | Glenview | Illinois | 60026 | — |
| GI Alliance (PFT) | Gurnee | Illinois | 60031 | — |
| Illinois Gastroenterology Group-Gurnee (Patients Seen; IP Delivered) | Gurnee | Illinois | 60031 | — |
| Medical Eye Services LTD (Ophthalmoscopy with OCT) | Gurnee | Illinois | 60031 | — |
| North Shore Endoscopy Center (Endoscopy) | Lake Bluff | Illinois | 60044 | — |
| Libertyville Imaging Center (Diagnostic Imaging) | Libertyville | Illinois | 60048 | — |
| Clark Memorial Health (PFTs) | Jeffersonville | Indiana | 47130 | — |
| One Anesthesia, AACC Division | Jeffersonville | Indiana | 47130 | — |
| Baptist Health Floyd (PFTs) | New Albany | Indiana | 47150 | — |
| Gastroenterology Health Partners, PLLC, (IP) | New Albany | Indiana | 47150 | — |
| John Kenyon Eye Center (OCT) | New Albany | Indiana | 47150 | — |
| One Anesthesia, PLLC | New Albany | Indiana | 47150 | — |
| Physicians Medical Center (Endoscopies) | New Albany | Indiana | 47150 | — |
| Quest | Lenexa | Kansas | 66219 | — |
| Cotton O'Neil Clinic (OCT Procedure Only) | Topeka | Kansas | 66606 | — |
| Cotton O'Neil Clinic (PFT Procedure Only) | Topeka | Kansas | 66606 | — |
| Cotton O'Neil Clinical Research Center, Digestive Health | Topeka | Kansas | 66606 | — |
| Acadiana Endoscopy Center, Inc | Lafayette | Louisiana | 70503 | — |
| Acadiana Gastroenterology Associates | Lafayette | Louisiana | 70503 | — |
| Combined Gastro Research, LLC | Lafayette | Louisiana | 70503 | — |
| Gastroenterology Clinic of Acadiana (IP address) | Lafayette | Louisiana | 70503 | — |
| Lafayette General Endoscopy Center | Lafayette | Louisiana | 70503 | — |
| Lafayette Family Eye Care | Lafayette | Louisiana | 70508 | — |
| M Health Fairview Clinics and Surgery Center | Minneapolis | Minnesota | 55455 | — |
| M Health Fairview University of Minnesota Medical Center | Minneapolis | Minnesota | 55455 | — |
| University of Minnesota Health Clinical research unit | Minneapolis | Minnesota | 55455 | — |
| University of Minnesota Health Opthalmology Clinic | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Celerion, Inc. | Lincoln | Nebraska | 68502 | — |
| Del Negro & Senft Eye Associates | Brick | New Jersey | 08723 | — |
| Allied Health Clinical Research Organization, LLC (IP Address) | Brick | New Jersey | 08724 | — |
| Seashore Surgical Institute | Brick | New Jersey | 08724 | — |
| Shore Pulmonary, PA | Brick | New Jersey | 08724 | — |
| Allied Health Clinical Research Organization, LLC | Freehold | New Jersey | 07728 | — |
| Del Negro & Senft Eye associates | Neptune City | New Jersey | 07753 | — |
| Del Negro & Senft eye Associates | Red Bank | New Jersey | 07701 | — |
| lnvestigational Drug Services, University of North Carolina Hospitals (IP storage address) | Chapel Hill | North Carolina | 27514 | — |
| UNC Clinical Research Eastowne | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals Pulmonary Function Lab (PFT and DLCO procedures only) | Chapel Hill | North Carolina | 27514 | — |
| University of North Carolina - Memorial Hospital | Chapel Hill | North Carolina | 27514 | — |
| UNC Endoscopy Center at Meadowmont | Chapel Hill | North Carolina | 27517 | — |
| UNC Hospitals Pulmonary Specialty Clinic (PFT and DLCO procedures only) | Chapel Hill | North Carolina | 27517 | — |
| UNC Kittner Eye Center (OCT procedure only) | Chapel Hill | North Carolina | 27517 | — |
| Clinical and Translational Research Center Outpatient Unit | Chapel Hill | North Carolina | 27599-7064 | — |
| Duke Medical Plaza North Duke Street | Durham | North Carolina | 27704 | — |
| Duke Eye Center | Durham | North Carolina | 27705 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Investigational Drug Services (Pharmacy) | Durham | North Carolina | 27710 | — |
| Coastal Research Institute | Fayetteville | North Carolina | 28304 | — |
| Cumberland Research Associates, LLC | Fayetteville | North Carolina | 28304 | — |
| UNC Gastroenterology at Hillsborough | Hillsborough | North Carolina | 27278 | — |
| Brier Creek Medical Pavilion | Raleigh | North Carolina | 27617 | — |
| Geauga Sleep Center (PFT Only) | Chardon | Ohio | 44024 | — |
| Leon A. Reid, III, M.D. (OCT) | Cincinnati | Ohio | 45209 | — |
| Cincinnati Eye Institute (ophthalmic and OCT exams) | Cincinnati | Ohio | 45219 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45219 | — |
| Gastro Health Research | Cincinnati | Ohio | 45219 | — |
| Ohio GI and Liver Institute | Cincinnati | Ohio | 45219 | — |
| Tristate Endoscopy Center (Endoscopy) | Cincinnati | Ohio | 45219 | — |
| UC Health Hoxworth (ophthalmic and OCT only) | Cincinnati | Ohio | 45219 | — |
| UC Health Physicians Office Clifton (where subjects seen) | Cincinnati | Ohio | 45219 | — |
| UC Health Pulmonary (PFT Location) | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Medical Center Diagnostic Center (Endoscopy location) | Cincinnati | Ohio | 45219 | — |
| UC Health Pulmonary (Pulmonary Function Testing) | Cincinnati | Ohio | 45229 | — |
| Leon A. Reid, III, M.D. (OCT) | Cincinnati | Ohio | 45236 | — |
| New Horizons Clinical Research (PFT) | Cincinnati | Ohio | 45242 | — |
| University Endoscopy Center (Endoscopy location) | Cincinnati | Ohio | 45242 | — |
| UC Health/Division of Digestive Diseases (where subjects seen) | Cincinnati | Ohio | 45267 | — |
| Erdey Searcy Eye Group | Columbus | Ohio | 43213 | — |
| Ohio Gastroenterology Group | Dublin | Ohio | 43016 | — |
| Great Lakes Medical Research, LLC | Mentor | Ohio | 44060 | — |
| The Endoscopy Center of Lake County | Mentor | Ohio | 44060 | — |
| Vitreo Retinal Consultants (OCT only) | Painesville | Ohio | 44077 | — |
| Lake Pulmonary Associates (PFT only) | Willoughby | Ohio | 44094 | — |
| Retina Specialists of Ohio(OCT only) | Willoughby Hills | Ohio | 44094 | — |
| Norman Endoscopy Center | Norman | Oklahoma | 73071 | — |
| Digestive Disease Specialists, Inc. Endoscopy Lab | Oklahoma City | Oklahoma | 73112 | — |
| Digestive Disease Specialists, Inc. | Oklahoma City | Oklahoma | 73112 | — |
| Pulmonary Physicians of Oklahoma | Oklahoma City | Oklahoma | 73112 | — |
| Retinal Center of Oklahoma | Oklahoma City | Oklahoma | 73112 | — |
| Central Sooner Research | Oklahoma City | Oklahoma | 73118 | — |
| Johnston Eye | Oklahoma City | Oklahoma | 73120 | — |
| West Shore Endoscopy Center | Camp Hill | Pennsylvania | 17011 | — |
| Medical Arts Allergy,PC (PFT Only) | Harrisburg | Pennsylvania | 17109 | — |
| Farrel Opthalmology(OCT only) | Harrisburg | Pennsylvania | 17110 | — |
| Susquehanna Research Group, LLC | Harrisburg | Pennsylvania | 17110 | — |
| Harrisburg Eye Associates (OCT only) | Harrisburg | Pennsylvania | 17111 | — |
| Penn State Health Medical Group - Lemoyne (PFT only) | Lemoyne | Pennsylvania | 17043 | — |
| Investigational Drug Services | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Tower Health Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Berks Center for Digestive Health | Wyomissing | Pennsylvania | 19610 | — |
| Berks Schuylkill Respiratory Specialists "PFT Procedure Only" | Wyomissing | Pennsylvania | 19610 | — |
| Eye Consultants of Pennsylvania, PC "OCT Procedure Only" | Wyomissing | Pennsylvania | 19610 | — |
| Regional Gastroenterology Associates of Lancaster, Ltd. | Wyomissing | Pennsylvania | 19610 | — |
| Rapid City Medical Center, LLP | Rapid City | South Dakota | 57701 | — |
| Franklin Woods Community Hospital (PFT Only) | Johnson City | Tennessee | 37604 | — |
| Pulmonary Associates of ET/Jeff Farrow, MD - PFT only | Johnson City | Tennessee | 37604 | — |
| The Regional Eye Center - OCT only | Kingsport | Tennessee | 37660 | — |
| Tri-Cities Gastroenterology | Kingsport | Tennessee | 37663 | — |
| Vanderbilt GI Endoscopy Lab at One Hundred Oaks | Nashville | Tennessee | 37204 | — |
| Vanderbilt University Medical Center - GI Research Office | Nashville | Tennessee | 37212-1610 | — |
| Vanderbilt University Medical Center GI Endoscopy Lab | Nashville | Tennessee | 37232-5543 | — |
| Vanderbilt Eye Institute | Nashville | Tennessee | 37232 | — |
| Vanderbilt Pulmonary Medicine | Nashville | Tennessee | 37232 | — |
| Vanderbilt University Medical Center - Digestive Disease Center | Nashville | Tennessee | 37232 | — |
| Vanderbilt University Medical Center - Heart Station | Nashville | Tennessee | 37232 | — |
| Digestive Health Center (Endoscopy) | Dallas | Texas | 75231 | — |
| Precision for Medicine | Houston | Texas | 77054 | — |
| CHRJSTUS Santa Rosa Physicians Ambulatory Surgery Center-new Braunfels(Endoscopy) | New Braunfels | Texas | 78130 | — |
| Tyrus Schroeder (PFT) | New Braunfels | Texas | 78130 | — |
| The Eye Place Jenny Fan, OD (OCT Only) | Plano | Texas | 75074 | — |
| Pulmonary Medicine Consultants (PFT with DCLO only) | Richardson | Texas | 75082 | — |
| Advanced Imaging | San Marcos | Texas | 78666 | — |
| Central Texas Eye Center (OCT) | San Marcos | Texas | 78666 | — |
| CHRJSTUS Santa Rosa Physicians Ambulatory Surgery Center - San Marcos (Endoscopy) | San Marcos | Texas | 78666 | — |
| Bay Area Houston Endoscopy Center (Endoscopy) | Webster | Texas | 77598 | — |
| Coastal Eye Associates (OCT) | Webster | Texas | 77598 | — |
| GI Alliance (Patients Seen) | Webster | Texas | 77598 | — |
| Houston Lung and Sleep Clinic, PA (PFT) | Webster | Texas | 77598 | — |
| University of Utah Gastroenterology Division Research | Salt Lake City | Utah | 84108 | — |
| Huntsman Cancer Hospital | Salt Lake City | Utah | 84112 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| University Of Utah School Of Medicine | Salt Lake City | Utah | 84132 | — |
| Chesapeake Pulmonary and Critical Care Medicine (PFT Only) | Chesapeake | Virginia | 23320 | — |
| Gastroenterology Associates of Tidewater - Endoscopy Center | Chesapeake | Virginia | 23320 | — |
| Gastroenterology Associates of Tidewater | Chesapeake | Virginia | 23320 | — |
| Harman Eye Center (OCT only) | Forest | Virginia | 24551 | — |
| Lynchburg Pulmonary Associates, Inc. (PFT only) | Lynchburg | Virginia | 24501 | — |
| Blue Ridge Medical Research | Lynchburg | Virginia | 24502 | — |
| Wagner Macula and Retina Center (OCT only) | Norfolk | Virginia | 23322 | — |
| Wagner Macula and Retina Center (OCT only) | Norfolk | Virginia | 23502 | — |
| Sleep Specialists of Tidewater - Virginia Beach (PFT Only) | Virginia Beach | Virginia | 23464 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04682639, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2024 · Synced Nov 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04682639 live on ClinicalTrials.gov.