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Completed Phase 2 Interventional

Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

ClinicalTrials.gov ID: NCT04683848

Public ClinicalTrials.gov record NCT04683848. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 2:48 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2a, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to compare the efficacy and safety of intravenous (IV) infusions of MT-3921 to placebo in subjects with acute traumatic cervical spinal cord injury. Subjects meeting eligibility criteria will enter the 6-month double-blind period. Subjects will be randomized in a 2:1 ratio to receive MT-3921 or placebo in a double blind manner.

Study identification

NCT ID
NCT04683848
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Tanabe Pharma America, Inc.
Industry
Enrollment
72 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 26, 2021
Primary completion
Dec 23, 2024
Completion
Apr 8, 2025
Last update posted
Dec 15, 2025

2021 – 2025

United States locations

U.S. sites
15
U.S. states
14
U.S. cities
15
Facility City State ZIP Site status
University of California Irvine Orange California 92868
Tallahassee Neurological Clinic Tallahassee Florida 32308
Augusta University Augusta Georgia 30912
University of Kentucky Lexington Kentucky 40536
Spectrum Health Grand Rapids Michigan 49503
University of Mississippi Medical Center Jackson Mississippi 39216
Saint Louis University Hospital St Louis Missouri 63110
University of Nebraska Medical Center Omaha Nebraska 68198
Carolinas Rehabilitation Charlotte North Carolina 28203
University of Cincinnati Cincinnati Ohio 45219
Oregon Health and Science University - Center for Health & Healing Portland Oregon 97239
Brooke Army Medical Center in San Antonio Houston Texas 78234
The University of Texas Health Science Center at San Antonio San Antonio Texas 78229
Carilion Clinic Roanoke Virginia 24014
Medical College of Wisconsin - Froedtert Hospital Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04683848, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 15, 2025 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04683848 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →