A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration
Public ClinicalTrials.gov record NCT04684394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Multiple-Dose Study in Neovascular Age-related Macular Degeneration (nAMD) to Evaluate the Safety, Tolerability, Pharmacodynamics, Immunogenicity, and Clinical Effect of Repeat Intravitreal (IVT) Injections of GEM103 as an Adjunct to Standard of Care Aflibercept Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to investigate the safety and tolerability of GEM103 IVT injection + standard of care vs. sham + standard of care.
Study identification
- NCT ID
- NCT04684394
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 50 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 29, 2020 (Actual)
- Primary completion
- Jan 10, 2022 (Actual)
- Completion
- Feb 18, 2022 (Actual)
- Last update posted
- Oct 31, 2022
2020 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 13
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Gemini Clinical Trial Site 16 | Phoenix | Arizona | 85021 | — |
| Gemini Clinical Trial Site 11 | Campbell | California | 95008 | — |
| Gemini Clinical Trial Site 9 | Encino | California | 91436 | — |
| Gemini Clinical Trial Site 17 | Huntington Beach | California | 92647 | — |
| Gemini Clinical Trial Site 12 | Pasadena | California | 91107 | — |
| Gemini Clinical Trial Site 5 | Miami | Florida | 33143 | — |
| Gemini Clinical Trial Site 7 | Pinellas Park | Florida | 33782 | — |
| Gemini Clinical Trial Site 20 | Sarasota | Florida | 34239 | — |
| Gemini Clinical Trial Site 8 | Stuart | Florida | 34994 | — |
| Gemini Clinical Trial Site 18 | Winter Haven | Florida | 33880 | — |
| Gemini Clinical Trial Site 19 | Indianapolis | Indiana | 46290 | — |
| Gemini Clinical Trial Site 4 | Hagerstown | Maryland | 21740 | — |
| Gemini Clinical Trial Site 23 | Worcester | Massachusetts | 01605 | — |
| Gemini Clinical Trial Site 22 | Royal Oak | Michigan | 48073 | — |
| Gemini Clinical Trial Site 1 | Reno | Nevada | 89502 | — |
| Gemini Clinical Trial Site 2 | Asheville | North Carolina | 28803 | — |
| Gemini Clinical Trial Site 15 | Charlotte | North Carolina | 28210 | — |
| Gemini Clinical Trial Site 6 | Cincinnati | Ohio | 45219 | — |
| Gemini Clinical Trial Site 10 | Eugene | Oregon | 97401 | — |
| Gemini Clinical Trial Site 13 | Beaufort | South Carolina | 29902 | — |
| Gemini Clinical Trial Site 3 | Dallas | Texas | 75231 | — |
| Gemini Clinical Trial Site 21 | San Antonio | Texas | 78240 | — |
| Gemini Clinical Trial Site 14 | San Antonio | Texas | 78247 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04684394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 31, 2022 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04684394 live on ClinicalTrials.gov.