Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy
Public ClinicalTrials.gov record NCT04684511. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Phase III Study With a Long-Term, Open-Label Extension to Evaluate the Efficacy and Safety of TRM-201 (Rofecoxib) in Patients With Hemophilic Arthropathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, double-blind study to evaluate the efficacy and safety of TRM-201 (rofecoxib) versus Placebo in the treatment of patients with hemophilic arthropathy (HA) over a 12-week period (Part I) that is followed by a year-long (52 week) open-label extension (Part II) to further evaluate the safety and maintenance of efficacy of TRM-201.
Study identification
- NCT ID
- NCT04684511
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 1, 2021
- Primary completion
- Sep 27, 2022
- Completion
- Sep 27, 2022
- Last update posted
- Oct 26, 2022
2021 – 2022
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Orthopedic Hospital DBA Orthopedic Hemophilia Treatment Center | Los Angeles | California | 90007 | — |
| Center for Inherited Blood Disorders | Orange | California | 92868 | — |
| UC Davis Children's Hospital | Sacramento | California | 95817 | — |
| University of Colorado Hemophilia & Thrombosis Center | Aurora | Colorado | 80045 | — |
| Georgetown University Hospital - Medstar | Washington D.C. | District of Columbia | 20007 | — |
| University of Florida - Shands | Gainesville | Florida | 32610 | — |
| Clinical Trial Services, Corp | Miami | Florida | 33144 | — |
| Anchor Medical Research, LLC | Miami | Florida | 33176 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| Louisiana Center for Bleeding and Clotting Disorders | New Orleans | Louisiana | 70112 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| ECMC Hospital | Buffalo | New York | 14202 | — |
| Icahn School of Medicine at Mount Sinai. | New York | New York | 10029 | — |
| East Carolina University | Greenville | North Carolina | 27858 | — |
| Rainbow Babies and Children's Hospital | Cleveland | Ohio | 44106 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| North Texas Comprehensive Hemophilia Center | Dallas | Texas | 75390 | — |
| Gulf States Hemophilia and Thrombophilia Center | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 27 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04684511, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 26, 2022 · Synced Sep 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04684511 live on ClinicalTrials.gov.